Check solvent % - as suggested low solvent content means tight packing
means poor signal.
Check matthews coefficient ? Do you expect several molecules?
As suggested - does the model form an oligamer? ( You need to be careful
with these - sometimes you generate thm using both crystal and
non-crysta
Dear Madhurima,
Small protein structures can be very difficult to solve by MR due to an
unfavorable ratio between inter- and intra-molecular vectors in the pattersons.
I am currently also struggling with some data sets myself.
However, there are things you could (and should) try:
1) If you