Re: [ccp4bb] AW: [ccp4bb] Problem with MolRep

2017-02-09 Thread Eleanor Dodson
Check solvent % - as suggested low solvent content means tight packing means poor signal. Check matthews coefficient ? Do you expect several molecules? As suggested - does the model form an oligamer? ( You need to be careful with these - sometimes you generate thm using both crystal and non-crysta

[ccp4bb] AW: [ccp4bb] Problem with MolRep

2017-02-09 Thread Herman . Schreuder
Dear Madhurima, Small protein structures can be very difficult to solve by MR due to an unfavorable ratio between inter- and intra-molecular vectors in the pattersons. I am currently also struggling with some data sets myself. However, there are things you could (and should) try: 1) If you