Dear Patrick,
Thank you for the insight!
Regards
Kavya
On 2024-02-06 00:29, Patrick Shaw Stewart wrote:
>> is it logical to say that if the protein is highly charged (either negative
>> or positive), it is likely to be more soluble and resist crystallization due
>> to electrostatic repu
Dear Guillaume,
That is right, if not for cations it would not have been possible.
We will check with the surface entropy reduction. Since we are designing
inhibitors for it, we cannot afford to do to much modifications.
Thank you
Regards
Kavya
On 2024-02-06 03:49, Guillaume Gaullie