[ccp4bb] OT: Lunch with the FT: Martin Shkreli

So the infamous Martin Shkreli is captivated by X-ray crystallography. https://www.ft.com/content/693ad306-9b6d-11e6-8f9b-70e3cabccfae QUOTE "He speaks of his love of Shakespeare and magical realist literature, and describes how he is captivated by science and medicine. “I’ve never done any art,

Re: [ccp4bb] ligand binding and crystal form

Thank you all for responses. I have added my reply below. On 26 October 2016 at 17:02, Eleanor Dodson wrote: > Are your 3 crystals isomorphous, and do they all refine well? Yes, all C2221 crystal datasets refine to ~ 19/23 % > I guess you struck lucky with DS3 - as suggested it could be a differ

Re: [ccp4bb] ligand binding and crystal form

Hi Valentina, > I just solved a NCS-tetrameric (biological assembly is just a dimer) crystal > structures with ligand soak (same plate - same conditions). No density for > ligand is observed in the first map. In the 2nd, I have 1 ligand bound. In > the 3rd, I have 2 ligands bound. Is there any

[ccp4bb] ligand binding and crystal form

Hello all, I just solved a NCS-tetrameric (biological assembly is just a dimer) crystal structures with ligand soak (same plate - same conditions). No density for ligand is observed in the first map. In the 2nd, I have 1 ligand bound. In the 3rd, I have 2 ligands bound. Is there any reason for this