[ccp4bb] Hydrophobic hotspots

2017-07-26 Thread Hugh Morgan
Hi all, can anyone recommend a program for identifying hydrophobic (aggregation) hotspots using either the amino acid sequence and/or structural data. Thanks in advance for your help Hugh Ps. Have tried aggrescan but would like to try a few others and compare, ideally a more structural based p

[ccp4bb] Antibody modelling software

2017-03-24 Thread Hugh Morgan
Hi all, can anyone recommend some user friendly software for modelling antibodies. Commercial or academic is fine. Thanks in advance for the help. Hugh

[ccp4bb] Observation:parameter ratio

2009-09-23 Thread hugh morgan
Hi,     We are attempting to address a referees comment concerning our data/parameter ratio for a 3.4 A structure. Although the ratio is only 0.5, the R/Rfree is 25/29, which seems acceptable. Ideally I would like to include a reference showing a graph or table of data:parameter vs resolution b

[ccp4bb] Fructose 2,6 Bisphosphate

2009-09-01 Thread hugh morgan
Hi, We have been trying to obtain fructose 2,6 bisphosphate (F-2,6-BP) for quite sometime now. Sigma has been trying to synthesize F-2,6-BP for over a year now and has still not managed to produce large enough quantities. I would be very grateful if someone could recommend any other possibl

[ccp4bb] soft white paraffin

2008-11-27 Thread hugh morgan
Hi, I have just been informed that it is no longer possible to get the soft white paraffin, for sealing cover slips, from VWR any more. If anyone knows of an alternative supplier please let me know. Thanks in advance Hugh

Re: [ccp4bb] Software for Drawing Protein Secondary Structure

2008-08-22 Thread hugh morgan
Try stride.. http://webclu.bio.wzw.tum.de/cgi-bin/stride/stridecgi.py --- On Fri, 22/8/08, Buz Barstow <[EMAIL PROTECTED]> wrote: From: Buz Barstow <[EMAIL PROTECTED]> Subject: [ccp4bb] Software for Drawing Protein Secondary Structure To: CCP4BB@JISCMAIL.AC.UK Date: Friday, 22 August, 2008, 2:57