[ccp4bb] dmmulti cross-crystal averaging question

2012-09-21 Thread Garboczi, David (NIH/NIAID) [E]
We are working with two crystals. Both crystals have a domain that is not in the other. Both crystals have one domain that is the same in each. We'd like the average the one domain between the crystals, but leave the other domains unaveraged. How do we describe that to dmmulti? thanks, Dave

[ccp4bb] high purity DMSO?

2012-08-15 Thread Garboczi, David (NIH/NIAID) [E]
We're dissolving ligands in DMSO and then mixing with protein for co-crystals and soaking. We suspect that our DMSO may be impure or degraded. Does anyone know a source for high grade, high-purity DMSO? thanks, Dave --