[ccp4bb] A challenging Molecular replacement

2017-07-18 Thread CDaddy
I am very happy that our colleagues give a lot of valuable suggestions. Sometimes you need to select a good example to teach students. In this regard 5XQL seems a really unbelievable paradigm--poor data, rookie crystallographer, challenging molecular replacement and overnight accepted literatur

[ccp4bb] A challenging Molecular replacement

2017-07-17 Thread CDaddy
I am a structural biologist who is teaching X-ray crystallography. Recently I noticed that BrlR structure (5XQL) was solved using molecular replacement with a search model of very low similarity. I am very interested in this structure because I think this a very good example to show students how

[ccp4bb] Questionable Data collection and refinement statistics for 5XQL

2017-06-29 Thread CDaddy
Dear colleagues, I am really astonished by a recently released structure 5XQL. This structure was just published in BBRC with a super fast process (accepted overnight). Significant inconsistences were observed when I compared the Data collection and refinement statistics in the paper and at PD