Agree with Tim's idea. Generating a composite omit map to see if your
solution is correct (or at least some part is correct if conformational
difference exists between model and your protein).
Bingfa
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表 Tim Grue
Dear Jobi,
For a crystal which is big in size(0.2-0.3mm is pretty big) while diffract
poorly, dehydration (increase concentration of the precipitant slowly) is a
good choice to improve diffraction, especially for those tends to crack during
cryo.
Also those regular optimization approaches: Add
