Scientific Director, Cal-Cryo. We are looking for an outstanding
microscopist to run our cryo-EM facility (two Krioses and an Arctica),
increase training, engagement, and collaboration on campus, expand our user
base, and join our community of cutting edge cryo-EM researchers.
tinyurl.com/ykasna3p
Dear all,
Please join the NIH supported CryoEM centers at our next CryoEM Current
Practices webinar.
Time: Thursday, January 30, 2025 at 9 AM pacific / 12 PM eastern time
Speaker: Rob Miller, Postdoctoral associate in the Davis Lab, MIT (Ando Lab
Alumni, Cornell)
Title: Mechanism of Nucleotide
Dear all,
a bit of a background follow-up to this:
On Tue, Jan 14, 2025 at 09:37:44AM -0500, Yong Tang wrote:
> I do understand PDBe offers electron density maps (8hbk.ccp4 and
> 8hbk_diff.ccp4 separately)- is that our go-to nowadays when we would like
> to inspect the maps of any particular PDB
Hello Marco,
I know you said you would prefer keeping the full-length protein. But have you
looked at an AlphaFold2 prediction? Ideally of the monomer and homo- and
hetero-dimers you mentioned. It’s often a good guide for construct design. If
you see a lot of “spaghetti” with low pLDDT, that mi
Dear all,
We have a postdoc position in the AstraZeneca protein structure team,
Gothenburg.
In this project you will design novel protein constructs and develop expression
and purification protocols. You will characterize the protein targets abilities
to bind coregulator peptides, DNA and next-
Hello,
Just thought I would add one actionable suggestion to Robbie’s good advice.
At least one program is well equipped to do this type of operations without
doing PDB file surgery: ChimeraX. See relevant documentation:
- the setattr command can set named "attributes" to atom selections, and c
Can we please start thinking a bit more in mmCIF please? Instead of hacking columns in PDB formatted files, perhaps we should look at molecular graphics programs' capabilities of colouring atoms or residues by a some column with label _somecategory.someitem. That way we are not hacking together cor
