Re: [ccp4bb] Structures refined ad mentula canis (this is Latin)

2024-10-29 Thread Pavel Afonine
Dear list members, the validation of TLS parameters used and refined for a particular model of a crystal structure was, at one point, the subject of thorough research, for example: >From deep TLS validation to ensembles of atomic models built from elemental motions. II. Analysis of TLS refinement

[ccp4bb] CBMS Lecture Series - Patrick Loll - OCTOBER 30 2024; 13:30 (EDT)

2024-10-29 Thread Stojanoff, Vivian
CORRECTION! date is October 30, 2024 @ 13:30 (EDT) - Please Share . You are cordially invited to join us . "How vancomycin-resistant enterococci recognize vancomycin" Patrick Loll Department of Biochemistry & Molecular Biology, Drexel Universit

[ccp4bb] CBMC Lecture Series - Patrick Loll - November 30 2024; 13:30 (EDT)

2024-10-29 Thread Stojanoff, Vivian
Please Share . You are cordially invited to join us . "How vancomycin-resistant enterococci recognize vancomycin" Patrick Loll Department of Biochemistry & Molecular Biology, Drexel University College of Medicine November 30, 13:30(EDT) To register for virtual attendance: https://bn

Re: [ccp4bb] Structures refined ad mentula canis (this is Latin)

2024-10-29 Thread a . perrakis
Dear all, As I somehow identify with the mention of "some ayatollahs” who perhaps underwent several rounds of meticulous refinement of demeanor, I fail to see any wrong to what Oliviero wrote. Oliviero, explains that a third party proclaimed that "unfortunately, the crystallographic programs be

Re: [ccp4bb] Structures refined ad mentula canis (this is Latin)

2024-10-29 Thread Robbie Joosten
Hear, hear! Although I like the Latin expression and the occasional rant in general, I fully agree with Gerlind's point. TLS refinement is a great tool and it can help even if the model segmentation is not biologically relevant. However, not biologically relevant may not necessarily mean that

Re: [ccp4bb] Structures refined ad mentula canis (this is Latin)

2024-10-29 Thread Gerlind Sulzenbacher
Dear Italo, It seems to me that the ccp4bb has always been a very gentle and empathic platform of exchange of ideas and offering a great deal of help to non-experts, "ignorants" as your friend calls them. I remember that in the late 90thies there were some ayatollahs, which have become gentl

Re: [ccp4bb] Structures refined ad mentula canis (this is Latin)

2024-10-29 Thread Doriano Lamba
Dear Oliviero, many thanks for your timely comment. I cannot agree more! Happy retirement! With all good wishes Doriano Il 2024-10-29 16:38 Italo Carugo Oliviero ha scritto: In a few months, I will retire, because my brain thinks it is still young but the rest of the body disagrees and think

[ccp4bb] Structures refined ad mentula canis (this is Latin)

2024-10-29 Thread Italo Carugo Oliviero
In a few months, I will retire, because my brain thinks it is still young but the rest of the body disagrees and thinks the brain is slightly senile. Of course, I will miss the protein structures very much, so unpredictable in their insolent beauty. I have devoted several years of my life to the

[ccp4bb] PostDoc position in the search for new drugs to fight H. pylori at the NOVA School of Science and Technology, Lisbon-Caparica, Portugal

2024-10-29 Thread Ana Luísa Moreira de Carvalho
We are pleased to announce an exciting opportunity for a Post-Doctoral researcher to join the NOVA School of Science and Technology (Caparica, Portugal) under the ERA Chair project, CryoEM@NOVA, funded by the HORIZON Europe Program. The successful candidate will carry out research into the pro