[ccp4bb] Crystallised PEG / Lys/ Gln

2022-11-03 Thread Joel Tyndall
Hi all, Quick question. I am well aware of seeing PEG crystallised with my protein in a circular shape around lysine residues. Can this also happen with GLN around the side chain nitrogen? Or even form an adduct? I see good evidence for at least the former option Happy Friday Joel Joel Tynda

[ccp4bb] open postodoctoral posiiton

2022-11-03 Thread Shaun Olsen
Dear Colleagues, A postdoctoral position is immediately available in the Wasmuth/Olsen Lab for a highly motivated individual interested in elucidating molecular mechanisms of oncogenic nucleoprotein complexes. These issues will be addressed using a multidisciplinary approach that includes cryo

[ccp4bb] Tenure Track Position in Cryo-EM

2022-11-03 Thread Martin Lawrence
Dear CCP4 Community, Montana State University (MSU) invites applications for a tenure-track faculty position in cryogenic electron microscopy. The position is formally a joint appointment between the Department of Chemistry and Biochemistry, and the Department of Microbiology and Cell Biology. T

Re: [ccp4bb] Another folding AI

2022-11-03 Thread Debanu Das
Amen. On Thu, Nov 3, 2022 at 5:19 AM Frank von Delft wrote: > Great, now we have two random number generators. > > > On 03/11/2022 12:10, David J. Schuller wrote: > > https://www.biorxiv.org/content/10.1101/2022.07.20.500902v2 > > Evolutionary-scale prediction of atomic level protein structure w

[ccp4bb] Deprecation of FTP File Download Protocol in the PDB Archive

2022-11-03 Thread Deborah Harrus
Dear all, The FTP protocol for file downloads has been losing popularity over the years in favor of HTTP/S. There are many advantages of HTTP/S including speed, statelessness, security (HTTPS), and better support. Importantly during the past 2-3 years the main web browsers (Chrome and Firefox)

Re: [ccp4bb] Another folding AI

2022-11-03 Thread Bryan Lepore
[ emphasis/bold font is mine]: “In general we look for a new law by the following process. First we guess it. Then we compute the consequences of the guess to see what would be implied if this law that we guessed is right. Then we compare the result of the computation to nature, with experiment

Re: [ccp4bb] Another folding AI

2022-11-03 Thread Frank von Delft
Great, now we have two random number generators. On 03/11/2022 12:10, David J. Schuller wrote: https://www.biorxiv.org/content/10.1101/2022.07.20.500902v2 Evolutionary-scale prediction of atomic level protein structure with a langu

[ccp4bb] Another folding AI

2022-11-03 Thread David J. Schuller
https://www.biorxiv.org/content/10.1101/2022.07.20.500902v2 Evolutionary-scale prediction of atomic level protein structure with a language model doi: https://doi.org/10.1101/2022.07.20.500902 Abstract Artificial intelligence has the