Hello All,
I am trying to solve a protein/nucleic acid (na) structure. The density for na
is poor and MR is less straightforward, so I used ModelCraft for automated
phasing, rebuilding and improving the electron density. It has built a partial
model for the complex, which looks somewhat reasona
Interested, but I am from Pharmaceutical Sciences background
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On Tue, 4 Oct 2022 at 10:19 pm, Andrew
Purkiss wrote: Hi Mark and Dave (who just
beat me to it),
Generally Sophos has been fine. However, I did get the following a
couple of weeks ago which So
Dear Petr and CCP4BB readers,
A lapse of attention led to a possibly obscure sentence: in the first
paragraph of our answer, the sentence "The input reflections to STARANISO
that are not present ..." should, for the avoidance of doubt, read: "The
input reflections to STARANISO that are not pr
Dear Petr,
Thank you for your reply and for inviting us to address some points!
Please find our replies below, "interleaved" with your questions.
On Tue, Oct 04, 2022 at 04:41:58PM +, Petr Kolenko wrote:
> Dear Gerard,
> A great remark! Thank you for starting this thread separately. I t
Dear Martin,
The concept of systematic absences is usually used for absences caused by the
crystal packing, e.g. glide planes etc. I guess that what you meant are
absences due to anisotropic cutoff. In the past, to get an Rmerge is low as
possible, people would cut there data at 2sigma, or even
Dear colleagues,
Firstly, I would like to thank Clemens, Claus, Ian and Gerard for the
very interesting analysis and remarks!
Similarly to Frank, I am wondering "whether any refinement program
properly extracts the high-resolution signal when there's anisotropy".
Poor completeness in high re
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corna...@al
Gerard, that's fascinating, thanks for the explanation.
I conclude in summary: nobody (including you) yet knows whether any
refinement program properly extracts the high-resolution signal when
there's anisotropy.
My (similar) question a few days ago was: /"Is that because of the
practicalit
Dear Clemens, Claus, Ian and Gerard,
since you ask for crowd sourcing, I'll give you my thoughts.
I think the term "anisotropy" is used in many ways to describe very
different events. It actually means the opposite of isotropy, so it is
coviniently used to describe a difference in resolution li
