Re: [ccp4bb] Unable to reduce the values of R-work and R-free

Hi Mudassar, The good new is that the data looks fine according to my experience and there are several ways to improve. The first thing I noticed in your aimless log is: "Anisotropic deltaB A^2: 50.24". This indicates severe anisotropy in your diffraction data. You may consider to use some ani

[ccp4bb] Postdoctoral position at OSU

Dear All, Applications are invited for a joint postdoctoral scientist position in the laboratories of Dr. Sarah Heissler and Dr. Krishna Chinthalapudi at the Ohio State University. The research project focuses on understanding the role of myosin motors and other cytoskeletal proteins in health a

[ccp4bb] Instruct webinar Structure meets function- webinar #17- registration open

Dear all, Featuring expert speakers from Instruct Centres across Europe, the Instruct-ERIC webinar series, Structure Meets Function, highlights some of the latest developments in structural bio

[ccp4bb] XChem access: Diamond AP32 Call for Proposals open until 30 March 2022

Hi all, Friendly reminder that the Diamond AP32 call for proposals (which includes XChem access between October 2022 and March 2023) is open until Wednesday 30th March at 17:00hrs UTC/GMT+1. Please check our webpage

Re: [ccp4bb] ligand binds to one molecule

Thank you all for your suggestions and useful comments, now I have better idea what could be the reason. We confirmed the ligand binding by testing it using MST. I guess the next step is to try co-crystallisation as you suggested. Best wishes, Shymaa From: CCP4

[ccp4bb] Postdoctoral Position - IBS - Grenoble - France

Dear CCP4 community, a postdoctoral research position financed by the National Research Agency is on offer by the Bacterial Pathogenesis Group (DR Andréa DESSEN) at the IBS (Institut de Biologie Structurale) in Grenoble. Our group focuses on the study of the various mechanisms used by the bac