Dear CCP4 Community,
Montana State University (MSU) invites applications for a tenure-track
faculty position in cryogenic electron microscopy. The position is
formally a joint appointment between the Department of Chemistry and
Biochemistry, and the Department of Microbiology and Cell Biology. T
Dear BB
It's been 20 months since we broadcast on this BB (and elsewhere) for
help to develop a SARS-CoV-2 Mpro inhibitor from XChem fragments. The
thing is still going strong, and in the open, with funding up to clinic.
Please do sign up if you're interested in drug discovery and
developme
Dear All,
The Cupido lab in the Department of Chemical Biology & Therapeutics at St Jude
Children Research Hospital (Memphis, TN) is seeking postdoctoral fellows who
wish to conduct structural and chemical biology research and gain experience as
independent researchers. These positions are core
Sanofi is one of the top pharmaceutical companies with more than 100,000 people
in 100 countries. We recently built a multidisciplinary team focusing on using
ML- and physics-based methods to accelerate design and engineering novel
protein therapeutics.
https://sanofi.wd3.myworkdayjobs.com/Sanof
We now have 160 delegates coming to the in-person part of the CCP4 Study
Weekend 2022.
As we still have space for another 60 people max (at 1m+ social distancing - UK
based delegates only), we have extended the early bird prices for the Study
Weekend until in-person registrations close on 30th
Hi Paul,
For me, dummy waters are waters placed in very early models, where it is not
yet clear whether the density belongs to a water, a rearranged side chain or a
ligand. In the course of the refinement process, it becomes clear to which
category the density really belongs. Especially for lar
Dear Paul,
with "dummy water" I refer to a water molecule, which I place at the center of
a (usually positive) difference electron density peak to be able to measure the
distances to the environment and decide, what the density actually might be. I
do that quite often. It could also be any othe
