Re: [ccp4bb] Why do large blobs show up in the pores of my crystal when I do refinement?

2021-03-31 Thread Eleanor Dodson
Blind almost always mean something is there. But your resolution is low. Scaling procedures st that resolution can cause misleading features to appear. Q1. How good is your Wilson plot? If you used the ccp4 data scaling etc it will have given you plots and comments. If you send s log file that wou

Re: [ccp4bb] Why do large blobs show up in the pores of my crystal when I do refinement?

2021-03-31 Thread Paul Emsley
On Wed, 2021-03-31 at 19:48 -0400, Jessica Besaw wrote: > > I once again am asking for your advice. ☺ I am trying to solve the > structure of an RBD:Fab complex. > > After molecular replacement, the density fits the model very well. > Looking at the overall crystal structure (by applying symmetr

[ccp4bb] New validation metric

2021-03-31 Thread Bernhard Rupp
Hi Fellows, here is a link to my latest paper on ligand validation. Due to embargo reasons I can display only the first and last page but the links in it are all active for those who are interested. http://www.ruppweb.org/Rupp_2021_Phys_Rev_Letters_126(13)_LDC.pdf Best, BR ---

[ccp4bb] Please register - Phenix Workshops - April 7 & 14

2021-03-31 Thread Paul Adams
Dear Colleagues, The Phenix developers will be holding an online *Phenix User Workshop on the 7th and 14th of April at 4-9pm PDT.* These times will work best for researchers in Asia and Australasia. The format of the workshop will be demos of the use of Phenix programs combined with slides to exp

Re: [ccp4bb] The oldest science

2021-03-31 Thread James Holton
Shiny! On 3/31/2021 10:36 AM, David Schuller wrote: https://www.haaretz.com/archaeology/.premium-somebody-in-the-kalahari-had-a-crystal-collection-105-000-years-ago-1.9670735 Somebody in the Kalahari Had a Crystal Collection 105,000 Years Ago -- ===

[ccp4bb] postdoctoral positions ICR London

2021-03-31 Thread Vlad Pena
Two postdoctoral positions are available in the lab of Vlad Pena, ICR, London Vlad Pena Lab | Institute of Cancer Research, London, UK Structural Biology / Protein-RNA complexes relevant for cancer Further information from: https://icr.tal.net/vx/appcentre-ext/brand-0/candidate/so/pm/1/pl/1/op

[ccp4bb] The oldest science

2021-03-31 Thread David Schuller
https://www.haaretz.com/archaeology/.premium-somebody-in-the-kalahari-had-a-crystal-collection-105-000-years-ago-1.9670735 Somebody in the Kalahari Had a Crystal Collection 105,000 Years Ago -- === All Things Serve the Beam =