This is hunch speak - not proper analysis, but it is possible to get huge
Fcalc, and hence large difference map terms, at low resolution by assuming
the solvent volume is a vacuum, not full of partially ordered water
molecules.
The Babinet scaling can do something to correct this but it is a very
>>And as we often end our beer-discussions - may be all protein space groups
>>are actually true P1, just close enough to satisfy the high symmetry rules ..
>>but this is getting a bit philosophical I know ..
Could we add that all crystals are twinned, just some are in such a way as to
be a pro
Dear All,
The next deadline for submitting proposals to the Stanford-SLAC Cryo-EM Center
(S2C2) is November 1, 2019.
The missions of the Stanford-SLAC Cryo-EM Center (S2C2) are:
1. to provide access to state-of-the-art cryo-EM instruments for data
collection towards atomic resolution struc
Hello everyone,
The Frederick National Laboratory for Cancer Research is looking for a
Scientist with experience in protein chemistry and structural biology. The
candidate will join the structural biology group within the NCI RAS
Initiative program and work on the protein-small molecule complexes.
Dear all,
This post is to bring your attention to a job opportunity of a scientist
position at Plexxikon Inc. We are looking for a highly motivated, structural
biologist with expertise in NMR. Please help to distribute this to anyone that
might be interested. Plexxikion is located in Berkel
Dear All
as has been pointed out, and as per usual, OS X updates seem to remove some of
the setup for XQuartz, which will cause most X11 based apps to stop working.
It is best to re-install XQuartz. This will work for an updated system that
had CCP4 previously installed on it. We have had a
Dear all,
regarding the "remaining strong differences" between measured data and
calculated SFs from a a finished (high res structure) I once investigated a
bit into this going back to images and looking up some extreme outliers.
I found the same - those were clear strong diffraction spots, not ice
