[ccp4bb] Job Opening for Institute Research Investigator

2019-09-06 Thread Troy Johnson
Dear all, This post is to bring your attention to a job opportunity for an Institute Research Investigator position at the University of Texas, MD Anderson Cancer Center (in Houston, Texas, USA). The mission of The University of Texas M. D. Anderson Cancer Center is to eliminate cancer in Texa

Re: [ccp4bb] Another difficult MR case

2019-09-06 Thread Oganesyan, Vaheh
Hi Napo, Just in case nobody suggested this option I want to add it. Very recently I’ve solved structure of Fab with 8 molecules per au. It wasn’t easy to do because some of tNCS were dropped by programs. After contacting the developer of MolRep Alexey Vagin and asking him to help understand wh

Re: [ccp4bb] Another difficult MR case

2019-09-06 Thread Eleanor Dodson
Crystals with many copies of a single model are indeed notoriously difficult to solve by MR. There is often a confusion between crystal symmetry and non-crystallographic symmetry, but in your case that wont happen - since the SG is P1. First thing i would check is the self-rotation function. Is th

[ccp4bb] CryoEM Scientist Position at Sosei Heptares Cambridge UK

2019-09-06 Thread Mathieu Rappas
We are seeking an experienced cryo-electron microscopy scientist to join the Biomolecular Structure group at our research facility on Granta Park, Cambridge, UK, working on GPCR structure determination to enable drug discovery efforts. At Sosei Heptares we are equipped with a ThermoFisher Glacios

[ccp4bb] Research technician position at IIMCB Warsaw

2019-09-06 Thread Almudena Ponce Salvatierra
Dear all, We have an open position for a Research technician in biochemistry and structural biology of RNAs and macromolecular complexes at the Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw. As a Research Technician, you w

Re: [ccp4bb] Another difficult MR case

2019-09-06 Thread Gerard Bricogne
Dear Napoleão, If you have such a large number of copies of the molecule in the asymmetric unit, you should perhaps try and see whether there is some orientational regularity in the way they are arranged by calculating a self-rotation function. Any such indication might enable you to filter s