[ccp4bb] move ligand to fit the density in coot

Hi all, I was solving a protein-ligand complex structure and got a molecular replacement solution with the protein as the search model and now trying to fit the ligand to the electron density in coot. It seems that the ligand needs to change conformation to fit the density well. So, I created the

[ccp4bb] repulsive effects of arginine

Hi everyone, I'm working on structure of an antibody that inhibits a receptor. The antibody doesn't induce any conformational change in the receptor and doesn't bind the ligand binding site. If we superimpose the receptor with antibody and ligand the only hindrance we find is a electrostatic repuls

[ccp4bb] International School of Crystallography - Erice (Italy) 2014 - Second announcement

The 47th Course of the International School of Crystallography: Structural Basis of Pharmacology: Deeper Understanding of Drug Discovery through Crystallography will be held in Erice (Italy) May 30 - June 8, 2014. More details are available below. An up-to-date speaker list and program can be