Re: [ccp4bb] Structural transmission of signal across a membrane

2013-09-24 Thread Edward A. Berry
Gloria Borgstahl wrote: Hello ccp4ers, I am helping a colleague develop a grant and have a vague recollection of structures of transmembrane protein receptors that signal across the membrane. Can anyone send me specific examples? Many thanks, G I think cytoplasmic and periplasmic domains of

Re: [ccp4bb] Structural transmission of signal across a membrane

2013-09-24 Thread David Briggs
Integrins? Loads of structures and models . On 24 Sep 2013 16:49, "Edward A. Berry" wrote: > Gloria Borgstahl wrote: > >> Hello ccp4ers, >> I am helping a colleague develop a grant and have a vague recollection of >> structures of >> transmembrane protein receptors that signal across the membran

Re: [ccp4bb] OT: Ribosomal processivity

2013-09-24 Thread Katherine Sippel
I forgot to mention that in this case gene optimization and eukaryotic expression don't help. It's a product of the protein sequence itself. On Tue, Sep 24, 2013 at 10:29 AM, Katherine Sippel < katherine.sip...@gmail.com> wrote: > Denizens of the bulletin board, > > I would like to tap into your

[ccp4bb] Structural transmission of signal across a membrane

2013-09-24 Thread Gloria Borgstahl
Hello ccp4ers, I am helping a colleague develop a grant and have a vague recollection of structures of transmembrane protein receptors that signal across the membrane. Can anyone send me specific examples? Many thanks, G

[ccp4bb] OT: Ribosomal processivity

2013-09-24 Thread Katherine Sippel
Denizens of the bulletin board, I would like to tap into your vast knowledge of all things protein expression. Is anyone aware of a cell line or even a transformable/transfectable construct that produces high processivity ribosomes. I.E. one that can translate to the end of difficult mRNA without

[ccp4bb] Job Posting: Software Release Engineer for SBGrid Consortium

2013-09-24 Thread Michelle Ottaviano
POSITION TITLE: Software Release Engineer II SBGrid Consortium, Harvard Medical School JOB SUMMARY: SBGrid Consortium at Harvard Medical School (www.sbgrid.org) is a collaboration to provide the structural biology community with support for research computing. The primary service offered by SBGr

[ccp4bb] Two Postdoctoral Research Assistants in Oxford

2013-09-24 Thread Susan Lea
We seek to appoint two Research Associates to undertake structural studies of the Tat protein transporter. The Tat system is a highly unusual protein transport pathway that moves folded proteins across the bacterial cytoplasmic membrane [Nature Rev.Microbiol. (2012) 10: 483]. The Tat system is r

[ccp4bb] Position available in biomolecular simulation

2013-09-24 Thread Martyn Winn
Hi all, We have an opening for a computational scientist within my group at Daresbury (Cheshire, UK) to provide core support to the EPSRC-funded High-End Computing (HEC) Consortium in biomolecular simulation. The post will support the consortium through porting and optimisation of a variety of

[ccp4bb] Postdoc position at Imperial College

2013-09-24 Thread Curry, Stephen
Please see the link below for details: http://www.jobs.ac.uk/job/AHH279/research-associate/

[ccp4bb] Workshop on the PDBx/mmCIF Data Exchange Format For Structural Biology (October 22, 2013) and PSI Workshop on Theoretical Model Archiving and Validation (October 21, 2013)

2013-09-24 Thread Torsten Schwede
*Workshop on the PDBx/mmCIF Data Exchange Format For Structural Biology* Center For Integrative Proteomics Research Rutgers, The State University of New Jersey Tuesday October 22, 2013 http://www.proteinmodelportal.org/workshop-2013/ The wwPDB has established PDBx/mmCIF as the new standard form

Re: [ccp4bb] tNCS: indexing and EP problems

2013-09-24 Thread Tim Gruene
-BEGIN PGP SIGNED MESSAGE- Hash: SHA1 Hi Nicolas, you need to make sure the SPACE_GROUP_NUMBER is set (not commented out) and different from 0 in order for UNIT_CELL_PARAMETERS to be taken into account. Additionally you can unset the refinement of the CELL in the respective REFINE(IDXREF