Dear all,
Plexxikon is a leader in the discovery and development of novel, small molecule
pharmaceuticals. The company has utilized its proprietary discovery platform to
successfully develop a portfolio of competitively differentiated clinical and
preclinical stage programs in a number of thera
Hi all-
I have 2 PDB files of the same protein (in slightly different states) and I
want to output a table of interactions (preferably hydrogen bonds, salt
bridges) that are unique to a structure i.e. Ser22 OG forms a hydrogen bond to
Lys25 NZ in structure 1 but not in structure 2. In other word
Shankar,
I would suggest to also set up a few plates with your protein in HEPES
instead of Tris. I once worked for months trying to improve tiny crystals
while my protein was in Tris, pH 7.4, to no avail. I got beautiful
crystals when I purified my protein in HEPES, pH 7.4, with everything else
I love this footnote from the JMB paper:
" Requests should be accompanied with a new 2400 ft reel of magnetic tape, and
a check or
purchase order for U.S. $34.30 made to the order of Brookhaven National
Laboratory, to cover
postage and handling. This charge is subject to change in the future."
Charlie is correct about who established the PDB in 1971
and I assume that it was their decision to use Diamond
format initially. When I started at the PDB in summer
1974 there already were 14 entries, in Diamond format.
Frances
===
While I cannot be sure about the format, the original PDB was the creation of
Edgar Meyer, Walter Hamilton, and Helen Berman. Hamilton was at Brookhaven,
which held the database until 1994. It passed to the Rutgers consortium in
1998. It is likely that the format, which hasn't changed appreciabl
Are you referring to the format that resembled "Diamond"
format (Bob Diamond, not the synchrotron) that we used at
the PDB for the first 100 or so entries. Or are you
referring to the format that everyone now refers to as
PDB format? I had to reprocess the first 100 entries
from the original for
Some spam for your Friday night: does anybody know who invented the PDB
file format originally?
(We're at the Study Weekend dinner, and Keith Wilson's memory has failed
us all...)
Dear all,
Thank you very much for all your helpful comments. I will try them and post
on the BB my results.
Best regards
Shankar
On Wed, Jan 2, 2013 at 11:59 AM, Sankaranarayanan Srinivasan <
texs...@gmail.com> wrote:
> Dear all,
>
> A very happy new year to all.
>
> I would appreciate some ex
We are offering RapiData 2013, the fifteenth offering of our popular course:
Rapid Data Collection and Structure Solving at the NSLS: A Practical
Course in Macromolecular X-Ray Diffraction Measurement
The course will be held 21-26 April 2013: http://www.bnl.gov/RapiData/.
Student
Dear (and hopefully still festive) all,
We would like to draw attention to an opportunity to join the structural
biology laboratory of Martin Noble and Jane Endicott in the Northern Institute
for Cancer Research, Newcastle University. This post, funded for up to 2 years
by the MRC/DPFS, is
Dear All
some people have asked if the talks will be archived.
We will make the majority of the talks available as sessions on this site
http://87.83.31.218/tcs/#page:recordingList&pageNumber:1
Unfortunately some of the talks contain sensitive material, so we will not be
archiving those talks.
Dear All -
We would have a position available for a Postdoctoral Scientist at the SGC
(Oxford University)
Nuffield Department of Medicine, Structural Genomics Consortium, Old Road
Campus Research Building, Roosevelt Drive, Oxford
The PDF will work in the epigenetic probe project working on
For the unfamiliar, like myself, the URL for VLC is mms://87.83.31.218/stfc
On a Mac: VLC -> File -> Open Network ... (enter URL above) then click Open
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