[Bioc-devel] Deseq2 and differentia expression

2014-07-10 Thread jarod...@libero.it
Hi there!!! I have did this code: SampleTable <-data.frame(SampleName=metadata$ID_CLINICO,fileName=metadata$NOME, condition=metadata$CONDITION,prim=metadata$CDT) ddHTSeq <- DESeqDataSetFromHTSeqCount(sampleTable=SampleTable,directory=" Count/", design= ~condition) # effetto dello mutazione ddHTSeq

Re: [Bioc-devel] Deseq2 and differentia expression

2014-07-10 Thread Michael Love
hi Jarod, On Thu, Jul 10, 2014 at 7:59 AM, jarod...@libero.it wrote: > Hi there!!! > > I have did this code: > SampleTable > <-data.frame(SampleName=metadata$ID_CLINICO,fileName=metadata$NOME, > condition=metadata$CONDITION,prim=metadata$CDT) > ddHTSeq <- DESeqDataSetFromHTSeqCount(sampleTable=S

[Bioc-devel] Announcement: C++/Mavericks Best Practices guide posted

2014-07-10 Thread Nathaniel Hayden
Dear Bioc developers, If you have not already seen the July Bioconductor newsletter, it is worth taking a look, specifically the section about Mac OS X Mavericks adoption: http://www.bioconductor.org/help/newsletters/2014_July/#new-mac-os-x-mavericks-build-machines As you probably know, the re

[Bioc-devel] range-directed metadata management

2014-07-10 Thread Vincent Carey
a new, more inclusive GWAS catalog is available (GRASP, from Andrew Johnson at NHLBI), with 6 million records and voluminous metadata (though it seems sparse and perhaps can be trimmed/reshaped) i made a GRanges and it takes 3 minutes to load. even after stripping all the metadata, a GRanges with

Re: [Bioc-devel] range-directed metadata management

2014-07-10 Thread Steve Lianoglou
Hi, On Thu, Jul 10, 2014 at 1:52 PM, Vincent Carey wrote: > a new, more inclusive GWAS catalog is available (GRASP, from Andrew Johnson > at NHLBI), with 6 million records and voluminous metadata (though it seems > sparse and perhaps can be trimmed/reshaped) > > i made a GRanges and it takes 3 mi

Re: [Bioc-devel] range-directed metadata management

2014-07-10 Thread Michael Lawrence
On Thu, Jul 10, 2014 at 2:16 PM, Steve Lianoglou wrote: > Hi, > > On Thu, Jul 10, 2014 at 1:52 PM, Vincent Carey > wrote: > > a new, more inclusive GWAS catalog is available (GRASP, from Andrew > Johnson > > at NHLBI), with 6 million records and voluminous metadata (though it > seems > > sparse

Re: [Bioc-devel] range-directed metadata management

2014-07-10 Thread Vincent Carey
On Thu, Jul 10, 2014 at 7:05 PM, Michael Lawrence wrote: > > > > On Thu, Jul 10, 2014 at 2:16 PM, Steve Lianoglou > wrote: > >> Hi, >> >> On Thu, Jul 10, 2014 at 1:52 PM, Vincent Carey >> wrote: >> > a new, more inclusive GWAS catalog is available (GRASP, from Andrew >> Johnson >> > at NHLBI),

[Bioc-devel] GOHyperGParams Minimum Size

2014-07-10 Thread Dario Strbenac
Hello, When doing a gene ontology analysis, it is common to remove gene sets that are small to avoid a problem of their statistics spuriously being significant. For example, I have a list of 681 significantly differentially expressed genes, but some expected overlap values are much smaller than