[Bioc-devel] BioC2019 Code of Conduct violation response

2020-03-09 Thread Levi Waldron
Dear developers, for your information, the Bioconductor Code of Conduct committee's response to a violation reported at BioC2019 has been posted at https://bioc2019.bioconductor.org/code_of_conduct. -- Levi Waldron Associate Professor Department of Epidemiology and Biostatistics CUNY Graduate

Re: [Bioc-devel] Class for differentially expressed genes?

2020-03-09 Thread Roman Hillje via Bioc-devel
Thank you for the responses so far! The idea behind this is that I don’t want to limit users to a certain DGE toolkit, may it be DESeq2, edgeR or frameworks specifically developed for single cell data such as muscat. I’d like to have a common structure that users can pour their results into (mo

Re: [Bioc-devel] Class for differentially expressed genes?

2020-03-09 Thread Constantin Ahlmann-Eltze
Hi Roman, I think it is probably also helpful to check out how DESeq2 and edgeR (two popular Bioconductor packages for differential expression analysis) have solved that problem: In DESeq2 for example the `nbinomWaldTest()` function calculates the differential expression and stores the results

Re: [Bioc-devel] Class for differentially expressed genes?

2020-03-09 Thread Vincent Carey
On Mon, Mar 9, 2020 at 6:58 AM Roman Hillje via Bioc-devel < bioc-devel@r-project.org> wrote: > Hi all, > > I was wondering if there is a class for results of differential gene > expression analysis. I couldn’t find anything generic. Perhaps it’s too > similar to a simple data frame, but I like th

Re: [Bioc-devel] Class for differentially expressed genes?

2020-03-09 Thread Shepherd, Lori
I would imagine a SummarizedExperiment would be the best option https://bioconductor.org/packages/release/bioc/html/SummarizedExperiment.html Lori Shepherd Bioconductor Core Team Roswell Park Comprehensive Cancer Center Department of Biostatistics & Bioinformatics Elm & Carlton Streets Buf

[Bioc-devel] Class for differentially expressed genes?

2020-03-09 Thread Roman Hillje via Bioc-devel
Hi all, I was wondering if there is a class for results of differential gene expression analysis. I couldn’t find anything generic. Perhaps it’s too similar to a simple data frame, but I like the idea of having a consistent format. I would imagine something that holds gene names, statistics (lo

Re: [Bioc-devel] Biostrings: unicode character ("compact ellipsis") in print()/show() output (2nd attempt, rephrased)

2020-03-09 Thread Hervé Pagès
Sorry for the inconvenience. I reverted this in Biostrings 2.55.5: https://github.com/Bioconductor/Biostrings/commit/567d8c30609783f87d7c641a98be1711ea47fb38 Using the compact ellipsis was an experiment in Bioc devel. Didn't really like it anyway (was hard to see). H. On 3/9/20 01:00, Ulri

Re: [Bioc-devel] Biostrings: unicode character ("compact ellipsis") in print()/show() output (2nd attempt, rephrased)

2020-03-09 Thread Ulrich Bodenhofer
Dear colleagues, Thanks for your replies to my message! A few more comments: * The issue I was reporting appeared on a Linux system (https://;www.r-project.org/nosvn/R.check/r-devel-linux-x86_64-debian-clang/apcluster-00check.html). * I agree that this is mainly a problem related to how La