[Bioc-devel] Bioconductor GSOC sponsorship?

2016-01-09 Thread Morgan, Martin
Hi -- Bioconductor has sometimes participated in Google Summer of Code (https://developers.google.com/open-source/gsoc/timeline?hl=en , https://developers.google.com/open-source/gsoc/faq#how_does_a_mentoring_organization_apply). If there is interest in the community to sponsor participation (f

Re: [Bioc-devel] Problem with seqnames of TwoBitFile from AnnotationHub

2016-01-09 Thread Hervé Pagès
On 01/09/2016 08:42 AM, Michael Lawrence wrote: I can understand the desire to avoid defining and enforcing our own standards on third-party data: it's error-prone, potentially confusing, etc. But the same is even more true of expecting the user to perform the mapping via some adhoc approach. It

Re: [Bioc-devel] Problem with seqnames of TwoBitFile from AnnotationHub

2016-01-09 Thread Tim Triche, Jr.
Also things like organismdbi don't seem to exist for organisms other than human, mouse, rat. So if you want to use that infrastructure for fly or worms, you're SOL at the moment. This is a highly topical discussion since many/most microarray probes can be profitably (in terms of knowledge, no

Re: [Bioc-devel] Problem with seqnames of TwoBitFile from AnnotationHub

2016-01-09 Thread Michael Lawrence
I can understand the desire to avoid defining and enforcing our own standards on third-party data: it's error-prone, potentially confusing, etc. But the same is even more true of expecting the user to perform the mapping via some adhoc approach. It's unfortunate that Ensembl does not follow the co

Re: [Bioc-devel] Problem with seqnames of TwoBitFile from AnnotationHub

2016-01-09 Thread Morgan, Martin
We switched to TwoBitFile with a recent ensembl release, thinking that it had better performance and other characteristics compared to the previous FaFile. The 'recipe' used to create the FaFiles did not explicitly trim the label; that appears to be something done by Rsamtools::indexFa and hence

Re: [Bioc-devel] Problem with seqnames of TwoBitFile from AnnotationHub

2016-01-09 Thread Rainer Johannes
Yes, using BSGenome would help in this case. In the long run I think it might be important to have this fixed, not necessarily for human, but for other species/genome builds for which there might not be an BSGenome package available; through AnnotationHub all GTF files and fasta files would be