Re: [Bioc-devel] Running Time of readBamGappedAlignmentPairs

2013-07-31 Thread Hervé Pagès
Hi Dario, Thanks for providing the file. The file has 55780092 records in it and yes it only contains primary alignments so this is the best situation for the pairing algorithm. Here are the timings I get for the readBamGappedAlignmentPairs() function (renamed readGAlignmentPairsFromBam() in de

Re: [Bioc-devel] the character to collapse the geneNames when using the disjointExons function with aggregateGenes=TRUE

2013-07-31 Thread Alejandro Reyes
Dear all, No problem from my side, I can adapt DEXSeq to those changes. Best regards, Alejandro Reyes Mike, Alejandro, I also wonder about getting rid of the 'exonID' metadata column. This is redundant with 'exonic_part_number'. Do you have a preference for keeping one or the other? Valer

Re: [Bioc-devel] the character to collapse the geneNames when using the disjointExons function with aggregateGenes=TRUE

2013-07-31 Thread Mike Love
Fine by me. I am currently rewriting parathyroidSE to benefit from this and the summarizeOverlaps changes. The workflow is greatly simplified. Mike On Jul 31, 2013, at 7:04 PM, Valerie Obenchain wrote: > Hi Nico, > > (Adding Mike and Alejandro.) > > Because disjointExons() came from DEXSeq

Re: [Bioc-devel] the character to collapse the geneNames when using the disjointExons function with aggregateGenes=TRUE

2013-07-31 Thread Valerie Obenchain
Mike, Alejandro, I also wonder about getting rid of the 'exonID' metadata column. This is redundant with 'exonic_part_number'. Do you have a preference for keeping one or the other? Valerie On 07/31/2013 10:04 AM, Valerie Obenchain wrote: Hi Nico, (Adding Mike and Alejandro.) Because dis

Re: [Bioc-devel] the character to collapse the geneNames when using the disjointExons function with aggregateGenes=TRUE

2013-07-31 Thread Valerie Obenchain
Hi Nico, (Adding Mike and Alejandro.) Because disjointExons() came from DEXSeq I wanted to preserve the behavior for backwards compatibility and familiarity to DEXSeq users. There are a couple of changes I'd like to make so disjointExons() is consistent with the other extractors in GenomicFea

Re: [Bioc-devel] shiny, Bioconductor, and reproducible research

2013-07-31 Thread Tim Triche, Jr.
Right this is what I meant with the captureOutput() snippet. Perhaps the whole reactive dispatch loop could be run to log instead of the clever force- directed graph of closures updating that Joe showed off after presenting Wednesday. No good deed goes unpunished, and this suggests that loggin

Re: [Bioc-devel] shiny, Bioconductor, and reproducible research

2013-07-31 Thread Kasper Daniel Hansen
I don't know how this actually works in practice. But conceptually, I think of moving a slider in an Shiny app as possibly executing some R code. It will be important for production quality code release that we are able to test that this code works in a easy and portable way. I realize we may not

Re: [Bioc-devel] shiny, Bioconductor, and reproducible research

2013-07-31 Thread Winston Chang
On Mon, Jul 29, 2013 at 4:46 PM, Dan Tenenbaum wrote: > Hi Winston, > > > > On Mon, Jul 29, 2013 at 2:39 PM, Winston Chang wrote: > > Hi everyone - > > > > Great to hear from you all on your thoughts about Shiny. I've tried to > > answer some of Dan's questions below... > > > > > >>> > >>> 1) Te

[Bioc-devel] the character to collapse the geneNames when using the disjointExons function with aggregateGenes=TRUE

2013-07-31 Thread Nicolas Delhomme
Hej Val, I believe that one is for you :-) When using the aggregateGenes=TRUE parameter of the disjointExons function, the gene names are separated by a "+" character. Is there a particular reason for that? The reason I'm asking is that in the "transcripts" column the transcripts ID are separat