[ccp4bb] DEADLINE IS APPROACHING (21st of February ) "Diffraction Methods in Drug Discovery and Development Symposium" | 4th of March 2025

[Shilova, Anastasya]

Dear colleagues,

We would like to invite you to the Bruker AXS  Symposium "Diffraction Methods 
in Drug Discovery and Development Symposium" at the Francis Crick Institute, 
London on the 4th of March 2025.

This half-day symposium will convene leading experts from academia and industry 
to explore the pivotal role of X-ray crystallography in drug discovery.
Confirmed speakers are from GSK, AstraZeneca UK, Astex Pharmaceuticals and 
leading UK universities.

When:  March 4, 2025
Where: The Francis Crick Research Institute, London, UK
The event is free of charge
Register now: Diffraction Methods in Drug Discovery and Development 




Best wishes,

Anastasya Shilova, Ph.D.

X-ray Division, Technical Sales Specialist

Bruker UK Ltd













-Bruker Confidential-



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[ccp4bb] 2025 Sealy Center for Structural Biology Symposium - Register NOW

[White, Mark]

You and your colleagues are cordially invited to join us for the 29th Annual 
Structural Biology Symposium to be held on Saturday April 5, 2025, Health 
Education Center on the UTMB Galveston Campus. The meeting is organized by the 
Sealy Center for Structural Biology & Molecular Biophysics and co-sponsored by 
the Keck Center for Computational & Structural Biology.

This year’s speakers include:

Kerry Bloom, Ph.D.

University of North Carolina, Chapel Hill

"Building springs with DNA"

Yifan Cheng, Ph.D.

University of California San Francisco

"Cryo-EM studies of integrin αvβ8 mediated L-TGF-β activation"

Yamini Dalal, Ph.D.

National Institutes of Health, NCI

"Interrogating chromatin dynamics using video speed atomic force microscopy"

Eduardo Perozo, Ph.D.
University of Chicago

"Prestin conformational dynamics and the molecular basis of the cochlear 
amplifier"

Jane Skok, Ph.D.

NYU Grossman School of Medicine

"A genome wide code to define cell-type specific CTCF binding and chromatin 
organization"

Li-av Segev-Zarko, Ph.D.
University of Texas Medical Branch

"Elucidating apicomplexan invasion: from macromolecular structures to 
biological function"


To register or for more information, visit:

https://www.utmb.edu/scsb/symposium


Abstract Deadline: Monday, March 24, 2025



Mark Andrew White, Ph.D.
Professor of Biochemistry & Molecular Biology,
Director, SCSB Macromolecular X-ray Laboratory
6.658A Basic Sciences L#35115, UTMB, Galveston, TX
https://xray.utmb.edu




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[ccp4bb] Call for Abstracts – Crystallographic Data Analysis & Processing Session at the ACA Meeting, July 18-23, 2025

[Dominika Borek]

Dear All,

Aaron Brewster and I are chairing the "Crystallographic Data Analysis 
and Processing" session at the 75th American Crystallographic 
Association Meeting in Lombard, IL (near Chicago) from July 18–23, 2025. 
We welcome abstract submissions for talks and posters. If you're 
interested, please submit your abstract at 
https://www.acameeting2025.com/.


March 31 – Deadline for oral abstracts & travel grant applications
April 30 – Deadline for poster abstracts

We invite contributions on novel algorithms, software tools, and 
workflows that enhance the accuracy, efficiency, and robustness of 
diffraction data analysis. Topics may include data collection 
optimization, error reduction strategies, data integration, and related 
advancements.


If you're interested in sponsoring our session, please reach out.

Best regards,

Dominika & Aaron


--
Dominika Borek, Ph.D. *** UT Southwestern Medical Center
5323 Harry Hines Blvd. *** Dallas, TX 75390-8816
214-645-9577 (phone) *** 214-645-6353 (fax)



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Re: [ccp4bb] Need help on optimizing my crystals

[Georg Mlynek]

Hi Cengiz Kaan Ferah,

you might want to look at

Successful sample preparation for serial crystallography experiments 
https://pmc.ncbi.nlm.nih.gov/articles/PMC6878878/


And I just stumbled about this one 
https://www.nature.com/articles/s41596-022-00777-5 (not yet read)


Br, Georg.


Am 2025-02-17 um 11:25 AM schrieb CENGIZ KAAN FERAH:

Hello,

I'm looking to grow the following crystals inside an eppendorf tube 
with increased quantity. How would I go about doing this? The crystals 
were grown with screening condition containing 0.2 M magnesium 
chloride hexahydrate, 0.1M HEPES Sodium pH:7.5 , 15% v/v PEG 400. 
Microbatch under oil was done as crystallization method using one part 
protein (0.83 uL), one part screening condition (0.83 uL). The photo 
of the crystals are attached below.


Thank you for your help.
Regards.
Cengiz Kaan Ferah



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[ccp4bb] Deadline approaching ! Postdoc position at Imperial College London/Francis Crick Institute

[Zhang, Xiaodong]

A reminder that deadline of Feb 20th is approaching.



Dear all

I am looking for postdocs to join my lab investigating signalling complexes and 
checkpoint response during DNA double-strand break repair.  I am looking for an 
enthusiastic structural molecular biologist with experience working with large 
protein complexes to join a team with diverse background and experiences.

My lab is currently seconded from Imperial College London to the Francis Crick 
Institute, which is one of the largest biomedical institutes in Europe 
(https://www.crick.ac.uk). My lab therefore has the unique privilege and access 
to the outstanding environment, facilities and opportunities provided by both 
Imperial College London (www.imperial.ac.uk) and the 
Francis Crick Institute.

To apply, please follow the link.

https://www.imperial.ac.uk/jobs/search-jobs/description/index.php?nPostingId=15397&nPostingTargetId=22820&id=PMMFK026203F3VBQB8NLOV4CQ&LG=UK&languageSelect=UK&mask=ext

For informal enquiries, please email 
xiaodong.zh...@imperial.ac.uk.


Xiaodong Zhang FRS

Imperial College London
Professor of Macromolecular Structure and Function
Section of Structural and Synthetic Biology
Department of Infectious Disease, Faculty of Medicine
London, SW7 2AZ
https://profiles.imperial.ac.uk/xiaodong.zhang

The Francis Crick Institute
Laboratory of DNA Processing Machines
1 Midland Road, London NW1 1AT
https://www.crick.ac.uk/research/labs/xiaodong-zhang




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