Re: [ccp4bb] request for applications

2024-04-02 Thread Pete Dunten
The obvious project worthy of such funding is crystallization in ultra low 
gravity.  Perfectly formed crystals are priceless and the basis for advances in 
structural biology.  Crystal growth on the ISS, in orbit 254 miles above the 
Earth, is considered growth in microgravity.  Now consider the Moon, at 238,855 
miles from Earth, where Earth's gravity, obeying the inverse square law, is 
much weaker.  Moving facilities from one massive body (the Earth) to another 
with its own gravity (the Moon), at great expense, may not seem a good idea at 
first blush.  Now consider tunneling to the center of the Moon, whose core is 
solid, and excavating a hollow, spherical cavity to house the crystallization 
lab.  One elegantly escapes the influence of lunar gravity.

Space X and the Boring Company are one step ahead of us, of course, and have 
already begun this 'PicoGrav' program on the dark side of the moon.  This note 
is meant to save everyone the trouble of putting together an application.  
History has shown that competing against industry is a losing strategy - the 
Human Genome Project being a fine example.  Stay tuned for updates from the 
astro-engineer on the Moon in charge of the project, Major Tom.  If you're 
lucky, you can enjoy a Space X resupply mission flyby of the ISS on its way to 
the Moon on one of the ISS webcams at 
-https://www.webcamtaxi.com/en/space/earth-live-cam1.html

Just the messanger, Pete



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[ccp4bb] Fwd: Sixth ESRF-INSTRUCT workshop on sample preparation for cryo-EM, May 28-30, 2024

2024-04-02 Thread David FLOT


-
Dear all,

Quick reminder that the last date to register for the ESRF-INSTRUCT 
hands-on workshop on sample preparation for cryo-EM is approaching (7th 
April).


The registration link is below.

https://survey.esrf.fr/index.php/849989?newtest=Y&lang=en

and the workshop webpage is

https://www.esrf.fr/home/events/conferences/content/area-events/esrf-events-list/instruct-cryo-em-workshop-1.html

Best regards,

Isai




 Forwarded Message 
Subject: 	[ccpem] Sixth ESRF-INSTRUCT workshop on sample preparation 
for cryo-EM, May 28-30, 2024

Date:   Fri, 15 Mar 2024 08:33:49 +0100
From:   Eaazhisai KANDIAH 
Reply-To:   Eaazhisai KANDIAH 
Organization:   ESRF
To: cc...@jiscmail.ac.uk



Dear colleague,

We are pleased to announce the sixth practical hands-on workshop on 
sample preparation for cryo-EM single particle data collection, 
jointly organized by the ESRF, EMBL Grenoble, and the IBS, continuing 
a series started in 2018. This 2.5 day workshop is aimed at PhDs, 
Postdocs and young scientists new to the field of single particle 
cryo-EM and will be held at the European Photon Neutron campus, 
Grenoble, France from M*ay 28^th to 30^th , 2024*. The course offers 
theoretical and practical aspects of sample preparation for single 
particle cryo-EM including prior quality control by negative staining. 
The participants will also learn the basics of grid screening and 
evaluation.


There is *no registration fee* and meals and accommodation during the 
workshop will be provided free of charge. However, participants should 
arrange and pay for their own travel to/from Grenoble. A maximum of 16 
participants will be selected and we will accept participants’ samples 
to be tested during the workshop, if the samples deemed suitable. In 
the case that you plan to bring your own sample, please clearly 
mention this in your cover letter, also indicating the importance of 
the project.


Application for the workshop is open 
 and the 
*deadline for application is April 7**^th **, 2024*. Successful 
candidates will be informed during the first week after the deadline. 
For more information, please consultINSTRUCT CRYO-EM WORKSHOP 
(esrf.fr) 
. 
For any inquiries, please write to cryo-em202...@esrf.fr


This is an in-person workshop and is co-funded by INSTRUCT (IBS).

Best wishes,

Isai (on behalf of the organising committee)

--

*Dr. Eaazhisai Kandiah*

CM01 beamline

https://www.esrf.fr/CM01

71 Avenue des Martyrs, 38000 Grenoble
Telephone: +33 476 882691
Email: eaazhisai.kand...@esrf.fr 




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[ccp4bb] CCPBioSim Industry Talk - Schrodinger 17 April 2024

2024-04-02 Thread Sarah Fegan - STFC UKRI
Hi all,

Free registration is open for our upcoming online Industry Talk by Márton Vass 
from Schrödinger at 14:00 British Summer Time on 17 April 2024. Details and 
registration link can be found at https://www.ccpbiosim.ac.uk/schrodinger2024.

Title: Structure-based target enablement with IFD-MD and FEP+

Abstract: AlphaFold2 and other recently developed machine learning protein 
structure prediction tools have sparked a new interest in enabling 
structure-based drug discovery for targets with no available relevant 
structural information. At Schrödinger, we are working towards understanding 
the possible uses and limitations of ML predicted structures and methods of 
refining them for accurate physics-based modelling.

We have previously shown that raw AlphaFold2 structures can provide virtual 
screening enrichments on a par with those achieved using apo protein structures 
and that this performance can be improved to similar levels seen with relevant 
holo structures using tools like Induced Fit Docking with Molecular Dynamics 
(IFD-MD).

The use of AlphaFold2 models can be extended further to ligand optimisation by 
combining IFD-MD refinement with FEP+, to derive models that are capable of 
recapitulating known SAR and which, subsequently, can be used for prospective 
free-energy calculations.

In addition to its use in on-target modelling, we've extended the use of IFD-MD 
to off-target modelling, where the use of a new and faster 'consensus IFD-MD' 
approach allows us to run the workflow on a larger number of input protein 
conformations. This method appears to show promise for enabling structure-based 
ADMET modelling by targeting commonly encountered off-targets, such as CYPs, 
PXR and hERG.



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[ccp4bb] 3-year PhD position in structural biology, Åbo Akademi University, Finland

2024-04-02 Thread Tiina Salminen
Dear all,

A 3-year PhD position is available within the IMMUDOCS doctoral pilot project 
in my lab at the Structural Bioinformatics Laboratory, Åbo Akademi University, 
Turku, Finland: Expanding Toolbox for Targeted Oncotherapy: Intercepting 
Clever-1.

Our research focuses on the structural, biochemical and biophysical analyses of 
proteins involved in inflammation, infection and cancer. We use a wide range of 
techniques including molecular biology, protein expression and purification, 
biochemical and biophysical protein interaction studies, X-ray crystallography, 
SAXS and Cryo-EM. The open PhD position is part of a larger interdisciplinary 
effort towards developing Clever-1-targeted immunotherapy. Novel cancer 
treatments complementary to the immune checkpoint targeting therapies are 
urgently needed to combat currently non-treatable cancers. Macrophage-targeted 
therapies, which break the immune-tolerance of tumors and assist activating 
host immune defense mechanisms, belong to these innovative treatments. 
Targeting Clever-1 with anti-Clever-1 antibody bexmarilimab interferes with the 
immunosuppressive properties of macrophages and slows the spread of cancer. As 
part of the project, we will determine the 3D structure for Clever-1 and 
elucidate its interactions with bexmarilimab at the atomic level to uncover 
inhibitory epitope. The obtained results will enable structure-based drug 
design of small molecular inhibitors expanding the toolbox for 
Clever-1-targeted oncotherapy.

We are looking for a self-motivated PhD student with good communication skills 
and a strong interest in structural biology, protein biochemistry, biophysics 
and structure-function relationship and a previous exposure to relevant 
research areas during their master education.


Applicants must have accomplished their Master's studies (or equivalent) on 
July 31 2024.


The application must be made online before April 15th, 2024: 
https://abo.rekrytointi.com/paikat/index.php?jid=780&key=&o=A_RJ&rspvt=ba2lzeepo68kg04g0kgsw044o80kccg




Do not hesitate to contact me if you have any questions.


Best wishes,

Tiina


**

Tiina A. Salminen, Professor

Head of Subject Cluster for Biochemistry and Cell Biology


Structural Bioinformatics Laboratory and InFLAMES Research Flagship Center

Biochemistry, Faculty of Science and Engineering

Abo Akademi University

Tykistökatu 6A

FI-20520 Turku

Finland




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Re: [ccp4bb] request for applications

2024-04-02 Thread Hekstra, Doeke Romke
Hi James,

With a budget of $1e12, I would like to ask for a database of fully ab initio 
QM simulations of proteins and systems of interest. I'd love to see equilibrium 
and non-equilibrium simulation, e.g. for photosystems I/II actually absorbing 
photons and responding thereto. I'd like to see actual enzyme catalysis happen. 
And understand when and where aromatic residues really shuffle around 
electrons.  How much we have missed by pretending that quantum phenomena are 
unimportant? We would also have some training data for accurate neural 
forcefields, instead of replicating the biases of existing forcefields. Would a 
trillion dollars do, including covering the renewable energy to offset the 
computing carbon footprint?

For only $5e8, recrystallizing the entire PDB is just a rounding error on the 
budget and obviously worth doing. I'd like to think that X-ray crystallography 
is a powerful technique. It's rather depressing to think that crystallization 
itself, rather than the phase problem or X-ray sources, is the biggest 
practical bottleneck to its use. 

My two cents,
Doeke


-Original Message-
From: CCP4 bulletin board  On Behalf Of Pete Dunten
Sent: Tuesday, April 2, 2024 3:49 AM
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] request for applications

The obvious project worthy of such funding is crystallization in ultra low 
gravity.  Perfectly formed crystals are priceless and the basis for advances in 
structural biology.  Crystal growth on the ISS, in orbit 254 miles above the 
Earth, is considered growth in microgravity.  Now consider the Moon, at 238,855 
miles from Earth, where Earth's gravity, obeying the inverse square law, is 
much weaker.  Moving facilities from one massive body (the Earth) to another 
with its own gravity (the Moon), at great expense, may not seem a good idea at 
first blush.  Now consider tunneling to the center of the Moon, whose core is 
solid, and excavating a hollow, spherical cavity to house the crystallization 
lab.  One elegantly escapes the influence of lunar gravity.

Space X and the Boring Company are one step ahead of us, of course, and have 
already begun this 'PicoGrav' program on the dark side of the moon.  This note 
is meant to save everyone the trouble of putting together an application.  
History has shown that competing against industry is a losing strategy - the 
Human Genome Project being a fine example.  Stay tuned for updates from the 
astro-engineer on the Moon in charge of the project, Major Tom.  If you're 
lucky, you can enjoy a Space X resupply mission flyby of the ISS on its way to 
the Moon on one of the ISS webcams at 
-https://www.webcamtaxi.com/en/space/earth-live-cam1.html

Just the messanger, Pete



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Re: [ccp4bb] request for applications

2024-04-02 Thread Hekstra, Doeke Romke
To clarify, the simulations would be money-intensive. The interpretation would 
(at first!) be people-intensive.

-Original Message-
From: CCP4 bulletin board  On Behalf Of Hekstra, Doeke 
Romke
Sent: Tuesday, April 2, 2024 9:00 AM
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] request for applications

Hi James,

With a budget of $1e12, I would like to ask for a database of fully ab initio 
QM simulations of proteins and systems of interest. I'd love to see equilibrium 
and non-equilibrium simulation, e.g. for photosystems I/II actually absorbing 
photons and responding thereto. I'd like to see actual enzyme catalysis happen. 
And understand when and where aromatic residues really shuffle around 
electrons.  How much we have missed by pretending that quantum phenomena are 
unimportant? We would also have some training data for accurate neural 
forcefields, instead of replicating the biases of existing forcefields. Would a 
trillion dollars do, including covering the renewable energy to offset the 
computing carbon footprint?

For only $5e8, recrystallizing the entire PDB is just a rounding error on the 
budget and obviously worth doing. I'd like to think that X-ray crystallography 
is a powerful technique. It's rather depressing to think that crystallization 
itself, rather than the phase problem or X-ray sources, is the biggest 
practical bottleneck to its use. 

My two cents,
Doeke


-Original Message-
From: CCP4 bulletin board  On Behalf Of Pete Dunten
Sent: Tuesday, April 2, 2024 3:49 AM
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] request for applications

The obvious project worthy of such funding is crystallization in ultra low 
gravity.  Perfectly formed crystals are priceless and the basis for advances in 
structural biology.  Crystal growth on the ISS, in orbit 254 miles above the 
Earth, is considered growth in microgravity.  Now consider the Moon, at 238,855 
miles from Earth, where Earth's gravity, obeying the inverse square law, is 
much weaker.  Moving facilities from one massive body (the Earth) to another 
with its own gravity (the Moon), at great expense, may not seem a good idea at 
first blush.  Now consider tunneling to the center of the Moon, whose core is 
solid, and excavating a hollow, spherical cavity to house the crystallization 
lab.  One elegantly escapes the influence of lunar gravity.

Space X and the Boring Company are one step ahead of us, of course, and have 
already begun this 'PicoGrav' program on the dark side of the moon.  This note 
is meant to save everyone the trouble of putting together an application.  
History has shown that competing against industry is a losing strategy - the 
Human Genome Project being a fine example.  Stay tuned for updates from the 
astro-engineer on the Moon in charge of the project, Major Tom.  If you're 
lucky, you can enjoy a Space X resupply mission flyby of the ISS on its way to 
the Moon on one of the ISS webcams at 
-https://www.webcamtaxi.com/en/space/earth-live-cam1.html

Just the messanger, Pete



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Re: [ccp4bb] request for applications

2024-04-02 Thread John R Helliwell
Oh, gosh. Pete, I am sorry but I had already submitted a proposal. As you say 
nanogravity is surely next up and then picogravity. While I am waiting for Elon 
to get back to me I have been looking into an ultimate brightness ‘top pocket 
synchrotron’. This single electron device has the smallest emittance we can 
get, then it passes through an undulator of alternating positive and negative 
ions. (A resemblance to a sodium chloride belies its its actual complexity).  
All best wishes,
John  

Emeritus Professor John R Helliwell DSc




> On 2 Apr 2024, at 09:03, Pete Dunten  wrote:
> 
> The obvious project worthy of such funding is crystallization in ultra low 
> gravity.  Perfectly formed crystals are priceless and the basis for advances 
> in structural biology.  Crystal growth on the ISS, in orbit 254 miles above 
> the Earth, is considered growth in microgravity.  Now consider the Moon, at 
> 238,855 miles from Earth, where Earth's gravity, obeying the inverse square 
> law, is much weaker.  Moving facilities from one massive body (the Earth) to 
> another with its own gravity (the Moon), at great expense, may not seem a 
> good idea at first blush.  Now consider tunneling to the center of the Moon, 
> whose core is solid, and excavating a hollow, spherical cavity to house the 
> crystallization lab.  One elegantly escapes the influence of lunar gravity.
> 
> Space X and the Boring Company are one step ahead of us, of course, and have 
> already begun this 'PicoGrav' program on the dark side of the moon.  This 
> note is meant to save everyone the trouble of putting together an 
> application.  History has shown that competing against industry is a losing 
> strategy - the Human Genome Project being a fine example.  Stay tuned for 
> updates from the astro-engineer on the Moon in charge of the project, Major 
> Tom.  If you're lucky, you can enjoy a Space X resupply mission flyby of the 
> ISS on its way to the Moon on one of the ISS webcams at 
> -https://www.webcamtaxi.com/en/space/earth-live-cam1.html
> 
> Just the messanger, Pete
> 
> 
> 
> To unsubscribe from the CCP4BB list, click the following link:
> https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1
> 
> This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing 
> list hosted by www.jiscmail.ac.uk, terms & conditions are available at 
> https://www.jiscmail.ac.uk/policyandsecurity/



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[ccp4bb] Postdoc Position in Structural and Functional Studies of Transmembrane Transporters @ Paz lab, HWI

2024-04-02 Thread Aviv Paz
The Paz lab at the Hauptman-Woodward Medical Research Institute (HWI) is 
seeking a highly motivated and talented postdoctoral researcher to study the 
function and structure of transport proteins. The position is fully funded, 
available immediately, and is based in Buffalo, NY. The successful candidate 
will contribute to a project aimed at elucidating the structural basis 
controlling the functions of medically relevant transporters using 
cryo-electron microscopy (cryo-EM) and/or X-ray crystallography and various 
biochemical, biophysical, and functional tools. The candidate will also be 
responsible for interpreting and modeling the functional results and structures.

We offer a stimulating and collaborative research environment with access to 
state-of-the-art facilities that enable extensive structure/function studies 
such as the National High-Throughput Crystallization Center and our 
Cryo-Electron Microscopy Center. The candidate is expected to work 
independently, keep meticulous records, and will have the opportunity to 
present their research at national and international conferences and to 
interact with scientists from a variety of disciplines.

Requirements:

•   A Ph.D. in structural biology, biochemistry, biophysics, or a related 
field.
•   Extensive experience and understanding of molecular biology, protein 
production, purification, biochemistry, and structural determination.
•   A proven record of scientific productivity, demonstrated by 
high-quality publications in peer-reviewed journals.
•   Excellent communication and teamwork skills.

HWI is a prominent independent center for structural biology research, with 
outstanding facilities, also managing the IMCA-CAT beamline 17-ID at the 
Advanced Photon Source at Argonne National Laboratory in Lemont, IL. The 
Institute has strong ties with its neighbors at the Jacobs School of Medicine 
at University at Buffalo and Roswell Park Comprehensive Cancer Center.

Application review will begin immediately, and the position will remain open 
until filled. The compensation level for this full-time position is $56,484 and 
includes a generous benefits package. To apply, please send a cover letter, a 
CV, and contact information for three references to a...@hwi.buffalo.edu.

HWI is an equal-opportunity employer and is committed to creating a diverse and 
inclusive environment for all employees.



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[ccp4bb] Resolution discrepancy between MTZ file and Refinement

2024-04-02 Thread venkatareddy dadireddy
Hi,

The resolution range in my MTZ file is 70.88 - 2.0 A. When I refined my
structure using REFMAC5, the resolution that it gives is 70.88 - 1.94 A,
the difference of 0.04 A. I also used Phenix.refine which gives the
resolution output as it is in the MTZ file. Again, EDS (validation report)
gives the right resolution. What could be the possible reason for this
discrepancy? I have the structure deposited in the Protein Data Bank and it
is on hold. Thank you in advance for your help.

Thank you,






*Venkatareddy Dadireddy,B1-10,Prof. S. Ramakumar's Lab,Dept. of
Physics,IISc, Banglore.Cell: 07259492227*



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Re: [ccp4bb] Crystallographic data table

2024-04-02 Thread Sharan Karade
Hi Marco,

If you want all this information, during data processing you have to scale
the data in two formats. One is merged, which you will use for the
structure determination and another file is unmerged, which you can use to
create the Table in Phenix, which typically gives all the information
you need.


Regards
Sharan

On Mon, Apr 1, 2024 at 1:44 PM Marco Bravo  wrote:

> Here is my data table for the processed data. Would the total reflections
> be the observed reflections summed together? Then the unique reflections
> summed together for the unique reflections? Also do I use the I/sigma value
> reported here for the high and lowest resolution shells for my table? I am
> not a phenix user typically but may need to for the table function.
>
>
> https://www.dropbox.com/scl/fi/kkl2fu816q5wae1q81u6f/summary.jpg?rlkey=oaz31dhdxoikstw85waan21wg&dl=0
>
> Thank you
> Marco
>
> 
>
> To unsubscribe from the CCP4BB list, click the following link:
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>
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>


-- 
Sharan Karade
Assistant Research Scientist
IBBR-UMD, 9600 Gudelsky Dr,
Rockville
Maryland 20850



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Re: [ccp4bb] Room temperature change from 25ºC to 20ºC

2024-04-02 Thread Katherine Sippel
In the Southern realms of the US at least, academic centers maintain room temperature at WSRT year round because “77°, ew gross.” In fact, the only time those air conditioners turn off is when we are struck by errant polar vertices and our power grids fail. Postdocs described the experience as sweltering. Cheers,KatSent from my iPhoneOn Apr 1, 2024, at 8:20 AM, David J. Schuller  wrote:






Looking forward to feedback from the Southern realms as to which should be higher; SSRT or WSRT.







===
 All Things Serve the Beam
 ===
 David J. Schuller
 modern man in a post-modern world
 MacCHESS, Cornell University
 schul...@cornell.edu




From: CCP4 bulletin board  on behalf of Nukri Sanishvili 
Sent: Monday, April 1, 2024 10:47 AM
To: CCP4BB@JISCMAIL.AC.UK 
Subject: Re: [ccp4bb] Room temperature change from 25ºC to 20ºC
 



Excellent idea, Mark!
I think the solution to your dilemma is rather straightforward: we introduce a Winter Standard Room Temperature (WSRT) and a Summer Standard Room Temperature (SSRT). This way, the folks from locales closer to the equator can always use SSRT, while those
 from more temperate climates can take advantage of using both WSRT and SSRT.
The added benefit of this approach will be inclusion of researchers closer to either of the poles (which, forgive me for saying it, you so egregiously omitted from your considerations). Similar to the tropics, they could use just one standard - WSRT.
Hope it helps your and so many young scientists' careers.
Best wishes,
Nukri

 






On Mon, Apr 1, 2024 at 9:29 AM Mark  wrote:



Room temperature change from 25ºC to 20ºC


As a member of the inter-society standards commission St-Incent I have been asked to take the bearings of the structural biology community regarding a proposal to lower the universally understood room temperature from 25ºC (77º Fahrenheit) to 20ºC (68º
 Fahrenheit). Obvious advantages would be less heating necessary for experiments at this standard temperature. Given that laboratories nowadays are not commonly heated to this high temperature anyway, it does appear to make sense.


Members of tropical and subtropical countries have already expressed opposition to the proposal, because they have to reach room temperature by cooling rather than heating, so for them the proposal would mean more CO2 emissions, not less.


Please express opinions to this list today, so that I have time to collate them before the local deadline of 28 December.






Mark J van Raaij
Dpto de Estructura de Macromoleculas, lab 20B
Centro Nacional de Biotecnologia - CSIC
calle Darwin 3
E-28049 Madrid, Spain






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Re: [ccp4bb] Resolution discrepancy between MTZ file and Refinement

2024-04-02 Thread Kay Diederichs
Hi Venkatareddy Dadireddy,

do the unit cell parameters of your MTZ file and PDB file agree exactly ?

Take for example a cell of (100,110,120,90,90,90) in the header of the MTZ 
file, 
and (97,110,120,90,90,90) in the CRYST1 line of the PDB file.

In this example, the (50,0,0) reflection would be at 2.0A resolution if using 
the cell from the MTZ file, 
but it would be at 1.94A resolution if calculating the resolution based on the 
cell from the PDB file.

So perhaps REFMAC5 takes the cell from the PDB file, and phenix.refine takes 
the cell from the MTZ?
I didn't check but it may be worth finding out. 

HTH,
Kay


On Tue, 2 Apr 2024 21:16:57 +0530, venkatareddy dadireddy 
 wrote:

>Hi,
>
>The resolution range in my MTZ file is 70.88 - 2.0 A. When I refined my
>structure using REFMAC5, the resolution that it gives is 70.88 - 1.94 A,
>the difference of 0.04 A. I also used Phenix.refine which gives the
>resolution output as it is in the MTZ file. Again, EDS (validation report)
>gives the right resolution. What could be the possible reason for this
>discrepancy? I have the structure deposited in the Protein Data Bank and it
>is on hold. Thank you in advance for your help.
>
>Thank you,
>
>
>
>
>
>
>*Venkatareddy Dadireddy,B1-10,Prof. S. Ramakumar's Lab,Dept. of
>Physics,IISc, Banglore.Cell: 07259492227*
>
>
>
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[ccp4bb] REMINDER -- EMBO practical course (8th-12th July, 2024) on time-resolved serial macromolecular crystallography (TR-SX) at French-Alpes

2024-04-02 Thread Shibom Basu

Dear Everyone!

This is a quick reminder that deadline for registration for our EMBO 
practical course on TR-SX is approaching in 2 weeks!


Our EMBO practical course on TR-SX will be held at beautiful 
French-Alpine valley of Grenoble, France, from *8*_*th – 12th July, 
2024*_. The course aims to train next generation researchers in the 
field of TR-SX with hands-on training from micro-crystallization, TR-SX 
data collection, processing up to difference electron density map. We 
have a diverse and excellent list of speakers/trainers from the field.


Please take a look at the course webpage: 
https://www.embl.org/about/info/course-and-conference-office/events/ser24-01/


Advanced PhD students, postdocs, or early career researcher in the field 
are highly encouraged to apply and we will select 20 participants based 
on motivational letters/CV. Accommodations and meals are fully covered 
for the participants.


Application deadline: *15th April, 2024.
*

The course will offer plenty of time for discussion and opportunities 
for interactions from all career levels. Distinct events are 
incorporated to help participants for network and further their 
opportunities.


Best,

*Scientific organizers Team
*

Oskar Aurelius, Gisela Branden, Shibom Basu, Arwen Pearson, and Daniele 
de Sanctis


--
Shibom Basu, PhD.
Staff Scientist
European Molecular Biology Laboratory (EMBL)
71 avenue des Martyrs, CS 90181,
38042 Grenoble Cedex 9
France
Ph: +33-(0)-4 76 20 78 75



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