Hi! It works with the epson2 backend, but I had to modify /etc/sane.d/epson2.conf to get it to work given the vendor/product code was unknown.
So Epson Stylus SX125 (0x04b8/0x085c) should be added to the list of scanners supported by epson2 1.0.22 at http://www.sane-project.org/sane-mfgs.html so that people don't have to edit the config file to make theirs work. The closest on the list in terms of product code is "Stylus SX410 Series" (0x04b8/0x0851). HTH, Gabriel