Given that the virtual appliance file formats seem to be somewhat 
standardized so that different virtual machine running software can 
export-import virtual appliances, the most hassle free solution for writing 
scientific papers that use Sage might be the 

http://files.sagemath.org/win/index.html

I would also like to point out that although as of 2016 the newest 
persistent memory type is the FRAM

http://archive.softf1.com/2015/electronics/2015_12_xx_downloaded_FRAM_Description_by_Texas_Instruments.pdf

most computers in the past used Flash, which means that at some point the 
older computers that originate from the era, where those old Linux 
distributions were in use, stop working due to the bitrot of the Flash 
memory at their various components, BIOS, microcontrollers, etc. Newest 
hardware might not, probably does not, have the backwards compatibility to 
the old hardware. A stellar illustration of that is that the software of 
the various old computers can be run only in "computer simulators" like 

http://www.worldofspectrum.org/
http://www.mess.org/
http://www.emulator-zone.com/
http://www.hercules-390.eu/
http://simh.trailing-edge.com/
http://www.villehelin.com/wzonka-lad.html
http://gxemul.sourceforge.net/

There's even one for the x86 PC:
http://jpc.sourceforge.net/home_home.html

(I could copy-paste more from my archive page at 
http://archive.softf1.com/lounge/links_2_other_archives/
)

That is to say, at some point using a virtual machine IS YOUR ONLY OPTION,
because the Flash memory of the old hardware bitrots away or the old 
hardware
fails by other means and the new hardware does not support
all the legacy mess.

Thank You for reading my comment. :-)

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