You'll probably want to take a look at the CRAN Task View, http://cran.r-project.org/web/views/ClinicalTrials.html
david freedman Paul Miller wrote: > > Hello Everyone, >  > Iâm a SAS user who has recently become interested in sequential clinical > trials designs. Iâve discovered that the SAS based approaches for these > designs are either too costly or are âexperimental.â So now Iâm > looking for alternative software. Two programs that seem promising are > SPLUS Seqtrial and R. >  > I recently obtained a 30 day trial for the SPLUS Seqtrial add-on and have > worked my way through most of the examples in the manual. Iâve also > gotten access to R, installed a package called gsDesign, and worked > through most of the examples in its documentation. >  > Although I donât yet have a good understanding of the various approaches > to sequential clinical trials designs, I thought that the gsDesign package > seemed very impressive. I also understand that there are several other R > packages that relate to sequential clinical trials designs, such as > AGSDest , GroupSeq, ldbounds, MChtest, PwrGSD, and Seqmon. Some of these > seem fairly comprehensive while others seem to focus on a single approach. >  > My questions center on the adequacy of SPLUS Seqtrial and the R Packages. > I was wondering if there is anyone out there who would be familiar enough > with these to comment on their relative merits. Will SPLUS Seqtrial or the > R packages allow me to do all the designs Iâm ever likely to need? If I > pay for SPLUS Seqtrial, will I get anything that I canât get using the > various R packages? Are any of the R packages comprehensive? Or would it > at least be possible to cover all the types of designs that are commonly > used by employing a variety of R packages? What kind of validation work > generally goes into an R package and how would this likely compare to the > sort of validation work that has gone into Seqtrial? >  > There may be other questions that I should be asking but havenât thought > of. >  > At any rate, if some of you would be willing to share some advice or > insights Iâd greatly appreciate it. >  > Thanks, >  > Paul > > > __________________________________________________________________ > The new Internet Explorer® 8 - Faster, safer, easier. Optimized for Y > er/ > [[alternative HTML version deleted]] > > > ______________________________________________ > R-help@r-project.org mailing list > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide > http://www.R-project.org/posting-guide.html > and provide commented, minimal, self-contained, reproducible code. > > -- View this message in context: http://n4.nabble.com/SPLUS-Seqtrial-vs-R-Packages-for-sequential-clinical-trials-designs-tp966071p966780.html Sent from the R help mailing list archive at Nabble.com. ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.