Dear R-colleagues, this is a question from a R-newbie medical doctor:
I am evaluating data on inter-observer-reliability in endoscopy. 20 medical doctors judged 42 videos filling out a multiple choice survey for each video. The overall-data is organized in a classical way: observations (items from the multiple choice survey) as columns, each case (identified by the two columns "number of medical doctor" and "number of video") in a row. In addition there is a medical doctor number 21 who is assumed to be a gold-standard. As measure of inter-observer-agreement I calculated kappa according to Fleiss and simple agreement in percent using the routines "kappam.fleiss" and "agree" from the irr-package. Everything worked fine so far. Now I'd like to calculate specificity, sensitivity and accuracy for each item (compared to the gold-standard), as these are well-known and easy to understand quantities for medical doctors. Unfortunately I haven't found a feasible way to do this in R so far. All solutions I found, describe calculation of specificity, sensitivity and accuracy from a contingency-table / confusion-matrix only. For me it is very difficult to create such contingency-tables / confusion-matrices from the raw data I have. So I started to do it in Excel by hand - a lot of work! When I'll keep on doing this, I'll miss the deadline. So maybe someone can help me out: It would be very convenient, if there is way to calculate specificity, sensitivity and accuracy from the very same data.frames I created for the calculation of kappa and agreement. In these data.frames, which were generated from the overall-data-table described above using the "reshape" package, we have the judging medical doctor in the columns and the videos in the rows. In the cells there are the coded answer-options from the multiple choice survey. Please see an simple example with answer-options 0/1 (copied from R console) below: video 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 6 6 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 1 0 1 1 0 1 1 0 0 0 1 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18 18 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 19 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 20 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21 21 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 22 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 23 0 1 0 0 1 0 1 0 0 1 0 0 1 1 0 0 1 0 0 0 0 24 24 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 0 1 0 0 1 25 25 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 0 0 0 0 0 26 26 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 27 27 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28 28 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29 29 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35 35 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37 37 0 1 1 0 1 0 0 1 0 0 0 0 1 1 1 0 1 0 0 1 1 38 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 39 39 0 1 0 0 1 0 0 1 0 1 1 0 1 1 0 0 1 1 0 1 1 40 40 1 1 1 1 1 0 1 0 0 0 0 1 1 1 1 0 0 1 0 0 1 41 41 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 42 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 What I did in Excel is: Creating the very same tables using pivot-charts. Comparing columns 1-20 to column 21 (gold-standard), summing up the count of values that are identical to 21. I repeated this for each answer-option. From the results, one can easily calculate specificity, sensitivity and accuracy. How to do this, or something similar leading to the same results in R? I'd appreciate any kind of help very much! Greetings from Munich, Felix ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.
