Hi Rui,thank you for your suggestion. 
but when I try the solution, I got message below:

Error in "MLH1" | "MSH2" :   operations are possible only for numeric, logical 
or complex types

does it mean, grepl can not work on character field?
Thanks,Kai    On Thursday, May 27, 2021, 01:37:58 AM PDT, Rui Barradas 
<ruipbarra...@sapo.pt> wrote:  
 
 Hello,

ifelse needs a logical condition, not the value. Try grepl.


CRC$MMR.gene <- ifelse(grepl("MLH1"|"MSH2",CRC$gene.all), "Yes", "No")


Hope this helps,

Rui Barradas

Às 05:29 de 27/05/21, Kai Yang via R-help escreveu:
> Hi List,
> I wrote the code to create a new variable:
> CRC$MMR.gene<-ifelse(grep("MLH1"|"MSH2",CRC$gene.all,value=T),"Yes","No")
>  
> 
> I need to create MMR.gene column in CRC data frame, ifgene.all column 
> contenes MLH1 or MSH2, then the MMR.gene=Yes, if not,MMR.gene=No
> 
> But, the code doesn't work for me. Can anyone tell how to fix the code?
> 
> Thank you,
> 
> Kai
>     [[alternative HTML version deleted]]
> 
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