Thank you Michael. 

I will clarify some more. The function in the first part of the code that I 
posted generates the simulated dataset for a cluster randomized trial from the 
simstudy package. 

I am not quite clear what you mean by placing it outside the loop. So the goal 
here is to create n = 1000 independent datasets with different (randomly drawn 
values from the specified normal distributions not shown) for all of the 
parameters. What I have tried to do is place the seed at the very top of all my 
code in the past, but what that does is it leads to the creation of a single 
dataset that gets repeated over and over n = 1000 times. Hence, there ends up 
being no variability in the data (and power estimates from the p-values given 
the stated and required power). 

Regarding the counter, is it correct in this instance that the loop will 
continue until n = 1000 iterations have successfully converged? I am not so 
concerned with counting failures.

Thank you.
Edward

On 2020-06-14, 6:46 AM, "Michael Dewey" <li...@dewey.myzen.co.uk> wrote:

    I am not 100% clear what your code is doing as it gets a bit wangled as 
    you posted in HTML but here are a couple of thoughts.
    
    You need to set the seed outside any loops so it happens once and for all.
    
    I would test after trycatch and keep a separate count of failures and 
    successes as the failure to converge must be meaningful about the 
    scientific question whatever that is. At the moment your count appears 
    to be in the correct place to count successes.
    
    Michael
    
    On 14/06/2020 02:50, Phat Chau wrote:
    > Hello,
    > 
    > I put together the following code and am curious about its correctness. 
My first question relates to the Monte Carlo simulations – the goal is to 
continue to iterate until I get n = 1000 simulations where the model 
successfully converges. I am wondering if I coded it correctly below with the 
while loop. Is the idea that the counter increments by one only if “model” does 
not return a string?
    > 
    > I would also like to know how I can create n = 1000 independent data 
sets. I think to do this, I would have to set a random number seed via 
set.seed() before the creation of each dataset. Where would I enter set.seed in 
the syntax below? Would it be in the function (as indicated in red)?
    > 
    > powercrosssw <- function(nclus, clsize) {
    > 
    >    set.seed()
    > 
    >    cohortsw <- genData(nclus, id = "cluster")
    >    cohortsw <- addColumns(clusterDef, cohortsw)
    >    cohortswTm <- addPeriods(cohortsw, nPeriods = 8, idvars = "cluster", 
perName = "period")
    >    cohortstep <- trtStepWedge(cohortswTm, "cluster", nWaves = 4, lenWaves 
= 1, startPer = 1, grpName = "Ijt")
    > 
    >    pat <- genCluster(cohortswTm, cLevelVar = "timeID", numIndsVar = 
clsize, level1ID = "id")
    > 
    >    dx <- merge(pat[, .(cluster, period, id)], cohortstep, by = 
c("cluster", "period"))
    >    dx <- addColumns(patError, dx)
    > 
    >    setkey(dx, id, cluster, period)
    > 
    >    dx <- addColumns(outDef, dx)
    > 
    >    return(dx)
    > 
    > }
    > 
    > i=1
    > 
    > while (i < 1000) {
    > 
    >    dx <- powercrosssw()
    > 
    >    #Fit multi-level model to simulated dataset
    >    model5 <- tryCatch(lme(y ~ factor(period) + factor(Ijt), data = dx, 
random = ~1|cluster, method = "REML"),
    >                       warning = function(w) { "warning" }
    >    )
    > 
    >    if (! is.character(model5)) {
    > 
    >      coeff <- coef(summary(model5))["factor(Ijt)1", "Value"]
    >      pvalue <- coef(summary(model5))["factor(Ijt)1", "p-value"]
    >      error <- coef(summary(model5))["factor(Ijt)1", "Std.Error"]
    >      bresult <- c(bresult, coeff)
    >      presult <- c(presult, pvalue)
    >      eresult <- c(eresult, error)
    > 
    >      i <- i + 1
    >    }
    > }
    > 
    > Thank you so much.
    > 
    > 
    > 
    >   [[alternative HTML version deleted]]
    > 
    > ______________________________________________
    > R-help@r-project.org mailing list -- To UNSUBSCRIBE and more, see
    > https://stat.ethz.ch/mailman/listinfo/r-help
    > PLEASE do read the posting guide 
http://www.R-project.org/posting-guide.html
    > and provide commented, minimal, self-contained, reproducible code.
    > 
    > 
    
    -- 
    Michael
    http://www.dewey.myzen.co.uk/home.html
    

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