Yes, I used LDheatmap just a moment... First you need to convert your matrix (ej. your geno file) to snp.matrix usin the package "chopsticks", web> https://bioconductor.org/packages/release/bioc/html/chopsticks.html.
This package is no in R library. You need use a sourse. Use this code> ## try http:// if https:// URLs are not supported source("https://bioconductor.org/biocLite.R") biocLite("chopsticks") Then, a example to convert your matrix (geno file) to snp.matrix and use LDheatmap function # Pass LDheatmap a snp.matrix object set.seed(1) #make an example matrix of genotypes, coded as 0, 1 2 copies of an index allele gdat<-matrix(rbinom(n=500,size=2,prob=.5),ncol=5) require(chopsticks) gdat<-as(gdat,"snp.matrix") library(LDheatmap) LDheatmap(gdat,genetic.distances=c(0,1000,3000,4000,10000)) I hope help you.. El miércoles, 3 de febrero de 2016, 18:08:46 (UTC-6), Val escribió: > > Thank you Bert, > > Yes I looked a this one and I was looking for if any one has used it or > not > before? My data set is different what they are showing in the paper > > > > > > On Wed, Feb 3, 2016 at 4:00 PM, Bert Gunter <bgunte...@gmail.com > <javascript:>> wrote: > > > Have you looked here (found immediately by an internet search!)? > > > > > https://cran.r-project.org/web/packages/LDheatmap/vignettes/LDheatmap.pdf > > > > Cheers, > > Bert > > > > > > > > Bert Gunter > > > > "The trouble with having an open mind is that people keep coming along > > and sticking things into it." > > -- Opus (aka Berkeley Breathed in his "Bloom County" comic strip ) > > > > > > On Wed, Feb 3, 2016 at 1:49 PM, Ashta <sew...@gmail.com <javascript:>> > wrote: > > > Hi all, > > > > > > I am looking for an R package that calculates a pair wise LD > > > (linkage disequilibrium) I came up with library(LDheatmap). has any > > > one used this library? I would appreciate if I get a help how to use > > > this library for my set of data.. > > > > > > > > > My data set look like > > > > > > Geno file > > > Name1 1 1 2 2 2 2 > > > Name2 2 2 2 2 2 2 > > > Name3 2 2 2 2 2 2 > > > Name4 2 2 2 2 2 2 > > > Name5 1 1 2 2 2 2 > > > > > > > > > NameN 1 1 1 2 2 2 2 > > > > > > > > > The other file is map file > > > Chromosome, SNP, Location (physical) > > > > > > > > > Thank you in advance > > > > > > ______________________________________________ > > > r-h...@r-project.org <javascript:> mailing list -- To UNSUBSCRIBE and > more, see > > > https://stat.ethz.ch/mailman/listinfo/r-help > > > PLEASE do read the posting guide > > http://www.R-project.org/posting-guide.html > > > and provide commented, minimal, self-contained, reproducible code. > > > > ______________________________________________ > > r-h...@r-project.org <javascript:> mailing list -- To UNSUBSCRIBE and > more, see > > https://stat.ethz.ch/mailman/listinfo/r-help > > PLEASE do read the posting guide > > http://www.R-project.org/posting-guide.html > > and provide commented, minimal, self-contained, reproducible code. > > > > [[alternative HTML version deleted]] > > ______________________________________________ > r-h...@r-project.org <javascript:> mailing list -- To UNSUBSCRIBE and > more, see > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide > http://www.R-project.org/posting-guide.html > and provide commented, minimal, self-contained, reproducible code. > ______________________________________________ R-help@r-project.org mailing list -- To UNSUBSCRIBE and more, see https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.