You are probably overfitting.

This *IS* a statistical and not an R issue, and so does not belong
here. You MAY get useful help by posting on the R-SIG-mixed-models
list, however. But PLEASE post in *plain text*, not HTML, as the
posting guide asks.

Cheers,
Bert
Bert Gunter

"The trouble with having an open mind is that people keep coming along
and sticking things into it."
-- Opus (aka Berkeley Breathed in his "Bloom County" comic strip )


On Tue, Feb 23, 2016 at 2:34 AM, Daniel Preciado <danp...@hotmail.com> wrote:
> Hello all,
>
> I posted this question also in Stackoverflow, but in hindsight I realise it 
> probably fits better here. I am trying to use lme() to fit and compare 
> different models to data from an experiment in a repeated measures design. My 
> dependent variable is response time (RT, in milliseconds); and I have 2 
> factors: F_A (2 levels) and F_B (3 Levels). For F_B, I have specified the 
> following contrasts:
> F_B_C1 <- c(1, -1, 0)      # Contrast prize 1 and 2 levels
> F_B_C2 <- c(1, 0, -1)      # Contrast prize 1 with Neutral (no prize)
> F_B_C3 <- c(1, 0, -1)      # Contrast prize 2 with Neutral (no prize)
> F_B_C4 <- c(1, 1, -2)      # Contrast prize with Neutral
> contrasts(Data$F_B, how.many=4) <- cbind(F_B_C1, F_B_C2, F_B_C3, F_B_C4)
> Conditions 1 and 2 are 2 levels of the same manipulation, condition 3 is a 
> neutral control. I am interested in the effect of each level (individually) 
> on RT, and overall in the difference between the experimental manipulation 
> (pooling the first 2 conditions of factor B) and the control condition (final 
> condition of factor B).
>
> I defined the lme() models step-wise, starting with a Baseline model, and 
> then updating that one to include each factor individually, and finally the 
> interaction:
> RT_Base <- lme(RT ~ 1, random = ~1|SubjID/F_A/F_B, data=Data, method="ML")  
> #Baseline model
> RT_F_A <- update(RT_Base, .~. + F_A)            #Baseline + F_A
> RT_F_B <- update(RT_F_A, .~. + F_B)             #(Baseline+F_A) + F_B
> RT_Full <- update(RT_F_B, .~. + F_A:F_B)        #Full model (+ interaction)
> However, when I execute the code involving F_B, I get an
> "Error in MEEM (...): Singularity in Backsolve at level 0, block 1).
> I can still inspect the results of the model, but I would like to understand 
> where is this error coming from, what does it mean, and how to avoid it. 
> Furthermore, I realized that if I reduce the amount of contrasts to the 
> default 2, the code runs without any error, so I can only assume that it has 
> something to do with the user-specified comparison pairs. Also, the specified 
> contrasts are not displayed (only the default first 2).
>
> I also read in some answer that the intercept needed to be suppressed in 
> order to prevent this error (by adding RT ~ 0+Factors to the model formulae). 
> I tried that, but it produces the same error.
>
> I would appreciate any feedback regarding this, Thanks!
>
>
>
>         [[alternative HTML version deleted]]
>
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