Jianling: 1. What models are you trying to fit? Details matter, and it is impossible to give a good answer without specifics.
2. In general terms, to do this one combines all the data and allows for "appropriate" changes in the model parameters for the different groups. For example, different intercepts, rate constants, etc. This is where the specifics matter. 3. This is really more a statistics than an R question, and you would probably do better to pursue these issues either with a local statistical resource or on a statistics site, like stats.stackexchange.com. Cheers, Bert Bert Gunter "Data is not information. Information is not knowledge. And knowledge is certainly not wisdom." -- Clifford Stoll On Wed, Sep 9, 2015 at 9:04 AM, Jianling Fan <fanjianl...@gmail.com> wrote: > Hello all, > > I am trying to fit my data to a nls model. I have many sets of data > and each can fit well for the curve. but I want to fit them at once by > sharing 2 of 3 parameters of the model. I know it is a typical global > curve fitting problem, but I don't know how to do it by R? > > Does anyone know any package for this?? > > Thanks a lot! > > > Julian > > ______________________________________________ > R-help@r-project.org mailing list -- To UNSUBSCRIBE and more, see > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide http://www.R-project.org/posting-guide.html > and provide commented, minimal, self-contained, reproducible code. ______________________________________________ R-help@r-project.org mailing list -- To UNSUBSCRIBE and more, see https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.