Hello.

I am trying to simulate recruitment in a randomized trial. Suppose I have three streams (strata) of patients represented by these data frames.

df1 <- data.frame(strat=rep(1,10),id=1:10,pid=1001:1010)
df2 <- data.frame(strat=rep(2,10),id=1:10,pid=2001:2010)
df3 <- data.frame(strat=rep(3,10),id=1:10,pid=3001:3010)

What I need to do is construct a data frame with all of these combined where the order of selection from one of the three data frames is randomized but once a stratum is selected patients are selected sequentially from that data frame.

To see what I'm looking to achieve, suppose the first five subjects were to come, in order, from strata (data frames) 1, 2, 1, 3 and 2. The expected result should look like this:

rbind(df1[1,],df2[1,],df1[2,],df3[1,],df2[2,])
   strat id  pid
1      1  1 1001
2      2  1 2001
21     1  2 1002
4      3  1 3001
22     2  2 2002

I hope what I'm trying to accomplish makes sense. Maybe I'm missing something obvious, but I really have no idea at the moment how to achieve this elegantly. Since I need to simulate many trial recruitments it needs to be general and compact.

I appreciate any advice.

Kevin

--
Kevin E. Thorpe
Head of Biostatistics,  Applied Health Research Centre (AHRC)
Li Ka Shing Knowledge Institute of St. Michael's
Assistant Professor, Dalla Lana School of Public Health
University of Toronto
email: kevin.tho...@utoronto.ca  Tel: 416.864.5776  Fax: 416.864.3016

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