On 06 Jan 2015, at 07:40 , Rune Haubo <rune.ha...@gmail.com> wrote:

> On 5 January 2015 at 21:08, Ben Bolker <bbol...@gmail.com> wrote:
>> Roger Coppock <rcoppock <at> cox.net> writes:
>> 
>>> 
>>> When will "R" implement the "se.fit" option to the
>>> predict.nls() function?  Is there some schedule?
>>> 
>> 
>>  I think this is unlikely to happen, ever (sorry).  The exact method
>> for finding confidence intervals on nonlinear fits would be
>> to compute likelihood profiles for each prediction, which would
>> be rather tedious.
> 
> I understand profile likelihoods for parameters, but what do you mean
> by a profile likelihood for yet unobserved observations, i.e.
> predictions?

For (pointwise) confidence intervals on a predicted value, you can in principle 
reparametrize so that the predicted value becomes a parameter which together 
with (k-1) of the original parameters characterize the model completely; then 
you profile over the (k-1) parameters. 

For predicting new observations, i.e. obtaining tolerance limits, things are 
trickier; presumably you should set up a test for whether a new observation can 
be assumed to come from the same model as the original data, then work out the 
test statistic (but against which alternative?) and the accceptance region 
would be the answer.

(There probably is a literature...)


> 
>> 
>>  Another reasonable approach would be to use bootstrapping (see
>> linked r-help thread below).
>> 
>>  An approximate approach would be to use the delta method.
>> 
>>  The nlstools package might be useful.
> 
> Alternatively the propagate package: it provides a function predictNLS
> that computes uncertainty measures for nls predictions using (first
> and second order) Taylor approximations as well as simulation methods.
> 
> I think the appropriateness of a simple (first order) Taylor/Delta
> method depends on the application. I can think of two important
> aspects: (1) if the model function is close to linear, you might be
> ok. (2) if you are interested in a prediction-type (rather than
> confidence) interval and the residual spread dominates the
> uncertainty, any inaccuracies in the model function uncertainty (where
> you apply the approximation) is swamped by the residual spread anyway.
> In a recent application on shelf life estimation that I worked on,
> both of these aspects were applicable and a simple approximation was
> fine.

Code to do this might be accepted. ("R" surely won't implement it all by 
itself...)

-pd

-- 
Peter Dalgaard, Professor,
Center for Statistics, Copenhagen Business School
Solbjerg Plads 3, 2000 Frederiksberg, Denmark
Phone: (+45)38153501
Email: pd....@cbs.dk  Priv: pda...@gmail.com

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