Michael:

Your parameter specification is probably over-determined, so that you have
an infinite set of parameters that give essentially the same solution
within numerical error. I would venture to guess that this will not be
fixable with alternative optimizers. It is up to you to provide a sensible
problem specification; failure to do so cannot be blamed on the optimizer.

Cheers,
Bert


On Thu, Sep 5, 2013 at 3:23 AM, Michael Meyer <spyqqq...@yahoo.com> wrote:

> Thanks for all replies.
> The problem occurred in the following context:
>
> A Gaussian one dimensional mixture (number of constituents, locations,
> variances all unknown)
> is to be fitted to data (as starting value to or in lieu of mixtools). A
> likelihood maximization is performed.
>
> I'll try to destill the code so that reproducible failure of L-BFGS-B
> occurs
> and post it here.
>
>
>
> Michael Meyer
>         [[alternative HTML version deleted]]
>
> ______________________________________________
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>



-- 

Bert Gunter
Genentech Nonclinical Biostatistics

Internal Contact Info:
Phone: 467-7374
Website:
http://pharmadevelopment.roche.com/index/pdb/pdb-functional-groups/pdb-biostatistics/pdb-ncb-home.htm

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