On Jul 25, 2013, at 12:27 PM, Marc Schwartz wrote: > > On Jul 25, 2013, at 2:11 PM, John Sorkin <jsor...@grecc.umaryland.edu> wrote: > >> Colleagues, >> Is there any R package that will allow one to perform a repeated measures >> Cox Proportional Hazards regression? I don't think coxph is set up to handle >> this type of problem, but I would be happy to know that I am not correct. >> I am doing a study of time to hip joint replacement. As each person has two >> hips, a given person can appear in the dataset twice, once for the left hip >> and once for the right hip, and I need to account for the correlation of >> data from a single individual. >> Thank you, >> John > > > > John, > > See Terry's 'coxme' package: > > http://cran.r-project.org/web/packages/coxme/index.html >
When I looked over the description of coxme, I was concerned it was not really designed with this in mind. Looking at Therneau and Grambsch, I thought section 8.4.2 in the 'Multiple Events per Subject' Chapter fit the analysis question well. There they compared the use of coxph( ...+cluster(ID),,...) withcoxph( ...+strata(ID),,...). Unfortunately I could not tell for sure which one was being described as superio but I think it was the cluster() alternative. I seem to remember there are discussions in the archives. -- David. > > You also might find the following of interest: > > http://bjo.bmj.com/content/71/9/645.full.pdf > > http://www.ncbi.nlm.nih.gov/pubmed/22226885 > > http://www.ncbi.nlm.nih.gov/pubmed/22078901 > > > > Regards, > > Marc Schwartz > > ______________________________________________ > R-help@r-project.org mailing list > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide http://www.R-project.org/posting-guide.html > and provide commented, minimal, self-contained, reproducible code. David Winsemius Alameda, CA, USA ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.
