I suspect you received no reply as no one knows what you mean by "global fit analysis." If you have some specific technical definition in mind, provide a reference. Better yet, SEARCH (see CRAN's Task Views).
If you are merely mis-referring to "goodness of fit" measures, than all R's modeling functions in all packages provide such measures, this is a statistics-- not an R -- question, and you need to do some reading or consult a local statistician, not pester this list further. Cheers, Bert On Tue, Jul 9, 2013 at 11:17 AM, Asan Ramzan <[email protected]> wrote: > I sending this again as I forgot to add a subject > > > Hello R-help > > Does anyone know if there is a package for global > fit analysis and if so how to use it. I am trying to calculate the Kd > value of a protein interacting with its ligand (When protein interacts > with ligand this effect a number of residues). The table below > shows with increasing concentration of ligand changes in three different > residues. > > Concentration res1 res2 res3 > 0 0 0 0 > 1.99167E-05 0.012978 0.020862 0.03032 > 3.95847E-05 0.019562 0.032288 0.048266 > 7.82652E-05 0.021842 0.036 0.05521 > 0.000115656 0.025274 0.043862 0.06398 > 0.000151801 0.029896 0.048762 0.075302 > 0.000186741 0.033544 0.053556 0.084334 > 0.000220516 0.035676 0.058964 0.0914 > 0.000274932 0.037834 0.061818 0.097096 > 0.000352021 0.040694 0.066216 0.100024 > 0.000422686 0.04329 0.070414 0.109974 > 0.000552238 0.045482 0.074646 0.116072 > 0.000777155 0.047062 0.07671 0.118722 > 0.0012 0.05345 0.08602 0.130344 > [[alternative HTML version deleted]] > > > ______________________________________________ > [email protected] mailing list > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide http://www.R-project.org/posting-guide.html > and provide commented, minimal, self-contained, reproducible code. > -- Bert Gunter Genentech Nonclinical Biostatistics Internal Contact Info: Phone: 467-7374 Website: http://pharmadevelopment.roche.com/index/pdb/pdb-functional-groups/pdb-biostatistics/pdb-ncb-home.htm ______________________________________________ [email protected] mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.
