On 8/23/12 7:37 AM, "David Lyon" <david_ly...@yahoo.com> wrote:
> Can someone show me some code to do normalization by the median of some > control genes for the example below? > Many Many Thanks in advance > > > This strategy selects a subset of genes (called ³control genes²) and makes the > median of their data distribution similar across arrays. > id1 id2 id3 > control1 0.8 0.7 0.6 > control2 0.6 0.2 0.4 > probe1 0.3 0.2 0.5 > probe2 0.4 0.9 0.7 > probe3 0.6 0.7 0.4 SuperCurve* has a normalization function that normalizes by median, variable slope, and housekeeping genes. But it's geared towards slightly larger problems... It's used in production by our Core Labs to process their RPPAs. <http://bioinformatics.mdanderson.org/main/SuperCurve:Overview> * Shameless plug ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.
