Dear Thomas, Thank you for the quick reply.
Might be the Bimodal/Biphasic behavior is due to the ODE model. Now I am working on "modMCMC" function of FME. This is strange this function sometimes works fine but other times I am getting following errors and warnings. Error in modCost(out, yobs, weight = "std") : error: cannot estimate weighing for observed variable: Y In addition: Warning messages: 1: In lsoda(y, times, func, parms, ...) : an excessive amount of work (> maxsteps ) was done, but integration was not successful - increase maxsteps 2: In lsoda(y, times, func, parms, ...) : Returning early. Results are accurate, as far as they go I have read through the manual also but couldn't figure out the error. The code works fine if I fix some of the parameter (pars) but it gives above errors if i pass all the parameters(pars). Can you explain why this is happening? -- View this message in context: http://r.789695.n4.nabble.com/How-to-find-best-parameter-values-using-deSolve-n-optim-tp4506042p4633100.html Sent from the R help mailing list archive at Nabble.com. ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.
