On Jul 28, 2011, at 3:33 PM, Vickie S wrote:


Hi,
I have a question about filterMicroRna in AgiMicroRna package function for filtering probes in Agilent microRNA dataset.

ddPROC = filterMicroRna(ddNORM.micro, dd, control = TRUE, IsGeneDetected = TRUE, wellaboveNEG = FALSE, limIsGeneDetected = 75, limNEG = 25, makePLOT = TRUE, target.micro, verbose = TRUE)

If in a dataset there are two or more sample replicates and in the step of filtering probes I want to exclude a probe only if gIsGeneDetected = 0 in all two or three sample replicates.

I don't think by 'filterMicroRna' function provides any option for this type of filtering.

Are there any suggestions ?

Are you sure these are not BioConductor questions? They have their own sandbox.

--

David Winsemius, MD
West Hartford, CT

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