Hi Vikas, Here is one way:
df <- read.table("summary.txt", header = TRUE) str(df) df[, "total"] <- rowSums(df[, 3:6]) df[, 3:6] <- apply(df[, 3:6], 2, function(x) x / df[, "total"] * df[, "new"] * 2) > head(df) V1 V2 CaseA CaseC CaseG CaseT new total 1 10 135344109 0 0 24 0 12 1 2 10 135344110 0 24 0 0 12 1 3 10 135344111 0 0 24 0 12 1 4 10 135344112 0 0 24 0 12 1 5 10 135344113 0 0 24 0 12 1 6 10 135344114 24 0 0 0 12 1 Note that I read the data in differently than you did. This matters. Cheers, Josh 2011/7/12 Bansal, Vikas <vikas.ban...@kcl.ac.uk>: > Dear all, > > I have a problem and it is very difficult for me to get a code. > I am reading a file(attached with this mail) using the code- > > df=read.table("summary.txt",fill=T,sep="",colClasses = "character",header=T) > and dataframe df is like this- > > V1 V2 CaseA CaseC CaseG CaseT new > 10 135344109 0 0 1 0 12 > 10 135344110 0 1 0 0 12 > 10 135344111 0 0 1 0 12 > 10 135344112 0 0 1 0 12 > 10 135344113 0 0 1 0 12 > 10 135344114 1 0 0 0 12 > 10 135344115 1 0 0 0 12 > 10 135344116 0 0 0 1 12 > 10 135344117 0 1 0 0 12 > 10 135344118 0 0 0 1 12 > > I want to apply a formula which is (number/total)*new*2. > where number is in column caseA,G,C,T and total is sum of these 4 columns.I > will explain with an example.the output of first row should be- > > V1 V2 CaseA CaseC CaseG CaseT new > 10 135344109 0 0 24 0 12 > > because sum of 3rd,4th,5th and 6th column is 1 for first row.and for case A,C > and T if we will apply above formula the answer will be zero (0/1)*12*2 which > is equal to 0 but for Case G- > (1/1)*12*2 which is equal to 24. > > > Can you please help me. > > > > > > Thanking you, > Warm Regards > Vikas Bansal > Msc Bioinformatics > Kings College London > ______________________________________________ > R-help@r-project.org mailing list > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide http://www.R-project.org/posting-guide.html > and provide commented, minimal, self-contained, reproducible code. > > -- Joshua Wiley Ph.D. Student, Health Psychology University of California, Los Angeles https://joshuawiley.com/ ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.