Hello all, I am having a problem with nls. I have such data as shown below,
foo<-
Dose var
0 0.000000
100 -1.318178
200 -1.562425
400 -3.579960
1200 -3.788662
however, when I call nls as shown below,
>foo.nls<-nls(var~Emax*(Dose^hill)/((EC50^hill)+(Dose^hill)),
+ start=list(Emax=-4,EC50=269,hill=1),trace=T,data=foo)
i get the response below.
1.759088 : -4 269 1
Error in numericDeriv(form[[3]], names(ind), env) :
Missing value or an infinity produced when evaluating the model
if i remove the hill variable, it works. can someone help me out with
what I am coding wrong.
Thanks,
Lanre
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