For the sake of comparison:
>>> def cod(x):
... tupple1 = ("abc", "def", "xyz")
... tupple2 = ("pqr", "tuv", "123")
... if x in tupple1:
... doStuff()
... elif x in tupple2:
... doOtherStuff()
...
>>> dis.dis(cod)
2 0 LOAD_CONST 7 (('abc', 'def', 'xyz'))
3 STORE_FAST 2 (tupple1)
3 6 LOAD_CONST 8 (('pqr', 'tuv', '123'))
9 STORE_FAST 1 (tupple2)
4 12 LOAD_FAST 0 (x)
15 LOAD_FAST 2 (tupple1)
18 COMPARE_OP 6 (in)
21 JUMP_IF_FALSE 11 (to 35)
24 POP_TOP
5 25 LOAD_GLOBAL 3 (doStuff)
28 CALL_FUNCTION 0
31 POP_TOP
32 JUMP_FORWARD 25 (to 60)
>> 35 POP_TOP
6 36 LOAD_FAST 0 (x)
39 LOAD_FAST 1 (tupple2)
42 COMPARE_OP 6 (in)
45 JUMP_IF_FALSE 11 (to 59)
48 POP_TOP
7 49 LOAD_GLOBAL 4 (doOtherStuff)
52 CALL_FUNCTION 0
55 POP_TOP
56 JUMP_FORWARD 1 (to 60)
>> 59 POP_TOP
>> 60 LOAD_CONST 0 (None)
63 RETURN_VALUE
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