John, If your file has the .py or .pyc extension on it, it should just run at the command line from its own directory, assuming your environment and path variables are set correctly.
I use NoteTab which has a different way of doing it, but basically you should be able to run: c:\mydir>script.py You don't need the python.exe on the commandline. rick -- http://mail.python.org/mailman/listinfo/python-list