Writing COM Servers is not hard http://www.python.org/windows/win32com/QuickStartServerCom.html
IronPython is the other way. Choose COM Server approach if you are using the a lot of standard library functions (as I recall IronPython is not complete here, yet). Definitely choose this approach if you are using C extensions to Python. IronPython is good for simpler Python tasks at this moment. Expect this to change in the future. Of course, there is always XML-RPC, SOAP, CORBA etc for language independence if you don't mind Client/Server setup. You can also write code in C# and drive it from Python. Check Python for .NET. -- http://mail.python.org/mailman/listinfo/python-list
