Sure, there's a difference. Consider how this program behaves. Quit only quits the mainloop, Destroy destroys the root widget. When you Quit, you can enter the mainloop again.
from Tkinter import * t = Tk() Button(t, command=t.quit, text="Quit").pack() Button(t, command=t.destroy, text="Destroy").pack() t.mainloop() t.mainloop() Jeff
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