Ask this question on the very active wxPython-users mailing list (http://lists.sourceforge.net/lists/listinfo/wxpython-users). For sure someone will help you out. If you don't want to write the code yourself, but use a visual gui designer I strongly recommend using wxGlade (http://wxglade.sourceforge.net/), which is very simple and neat. It uses sizers by default, which has the advantage that you're dialog box will be rescalable.
Stani -- SPE - Stani's Python Editor (ships btw with wxGlade) http://pythonide.stani.be -- http://mail.python.org/mailman/listinfo/python-list
