Steve- I recently ported version 1.3 of cpaint to python. Soon after version 2.0 was released and I haven't really looked at it since. The 1.3 stuff was really simple though if you understand cgi, then you just implement a endpoint for your request to call. The javascript side is really the only thing new (might be a little learning if you having done much js).
I think that more advanced ajax libraries like dojo or openrico are probably better suited to more complicated ajax use. Though they are more focused on the js frontend stuff. -- http://mail.python.org/mailman/listinfo/python-list